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Differences in T cells’ functional states determine resistance to cancer therapy（图）
T细胞 癌症治疗 耐药性
2023/6/6
Non-small cell lung cancer (NSCLC) is the most common type of lung cancer in humans. Some patients with NSCLC receive a therapy called immune checkpoint blockade (ICB) that helps kill cancer cells by ...
How A Tumor Grows Can Predict Response To Cancer Therapy（图）
Tumor Grows Predict Response Cancer Therapy
2018/1/10
Individual tumors respond differently to cancer drugs, if at all. Until now, it remained a mystery why tumors have different reactions to the exact same therapy. But a new study at the USC Viterbi Sch...
Inhibition of Ape1's DNA Repair Activity as a Target in Cancer: Identification of Novel Small Molecules that have Translational Potential for Molecularly Targeted Cancer Therapy
Cancer Chemotherapy Base Excision Repair DNA Repair
2015/5/25
The DNA Base Excision Repair (BER) pathway repairs DNA damaged by endogenous and exogenous agents including chemotherapeutic agents. Removal of the damaged base by a DNA glycosylase creates an apurini...
An exhaustive analysis has been conducted of more than 12,000 distinct proteins present in an often aggressive and difficult to treat form of breast cancer, called triple-negative breast cancer.The re...
Impact of gene technologies on personalised cancer therapy
gene technologies personalised cancer therapy
2015/3/26
Given that cancer is driven by inherited and acquired defects in our genetic code, the ability to profile genes and their activities has the potential to impact substantially on the prevention and tre...
A large number of monoclonal antibodies (mAbs) are currently
under investigation for the treatment of malignant diseases. To
date, a significant amount of experimental and clinical research
had bee...
UQ researcher Dr Kris Thurecht is developing new molecules to potentially improve the performance of cancer therapy by delivering drugs directly to cancers. Dr Thurecht was awarded a $90,000 UQ Founda...
Current status of tumor necrosis factor-related apoptosis-inducing ligand receptor (TRAIL-R) targeting cancer therapy
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) TRAIL receptor 1 (TRAIL-R1), TRAIL receptor 2 (TRAIL-R2) apoptosis KM mouseTM monoclonal antibody targeting therapeutics
2009/7/15
Monoclonal antibodies have already established a secure position as a very promising strategy for anti-tumor therapeutics. High specificity and high affinity are attractive characteristics of antibodi...
Compact Cancer-Therapy Particle-Delivery System Patented
Cancer-Therapy Particle-Delivery System
2009/5/20
UPTON, NY — As part of an effort to make high-precision particle cancer therapy accessible to more patients, a physicist at the U.S. Department of Energy’s (DOE) Brookhaven National Laboratory has dev...
Investigations of the Telomerase Template Antagonist GRN163L and Implications for Augmenting Breast Cancer Therapy
GRN163L Telomerase Breast Cancer
2015/5/21
Breast cancer is the second most common cancer among women in the US after skin cancer. While early detection and improved therapy has led to an overall decline in breast cancer mortality, metastatic ...
New book documents Massachusetts Institute of Technology breast cancer therapy
breast cancer Thermotherapy
2007/1/29
January 26, 2007，A breast cancer treatment based on MIT research originally intended for detecting missiles is documented in a new book by Alan J. Fenn, an MIT researcher and inventor of the technique...