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2023年9月5日,癌症研究领域权威期刊Cancer Research(IF: 11.2)在线发表了题为"Genetic variants that impact alternative polyadenylation in cancer represent candidate causal risk loci"的研究论文[1]。武汉大学公共卫生学院博士后李斌、博士生蔡祎旻和谌灿为本论文的共同第一...
Multiple myeloma is an incurable bone marrow cancer that kills over 100,000 people every year. Known for its quick and deadly spread, this disease is one of the most challenging to address. As these c...
Over the past decade, the approval of immune checkpoint inhibitors has revolutionized treatment for patients with advanced lung cancer, helping many live longer lives and improving overall survival fo...
In the five years since the FDA’s initial approval of chimeric antigen receptor (CAR) T cell therapy, Penn Medicine has gleaned 20 additional approvals related to drugs and techniques to treat or dete...
A novel cancer therapeutic, combining antibody fragments with molecularly engineered nanoparticles, permanently eradicated gastric cancer in treated mice, a multi-institutional team of researchers fou...
Treating cancer with combinations of drugs can be more effective than using a single drug. However, figuring out the optimal combination of drugs, and making sure that all of the drugs reach the right...
Over the past few decades, scientists have made great strides in understanding the genetic mutations that can drive cancer. For some types of cancer, these discoveries have led to the development of d...
Non-small cell lung cancer (NSCLC) is the most common type of lung cancer in humans. Some patients with NSCLC receive a therapy called immune checkpoint blockade (ICB) that helps kill cancer cells by ...
近日,上海市肿瘤研究所田华研究团队在国际著名肿瘤学期刊CancerResearch杂志在线发表了题为“ApositivefeedbackloopofAKR1C3-mediatedactivationofNF-κBandSTAT3facilitatesproliferationandmetastasisinhepatocellularcarcinoma”的研究论文。该研究揭示了AKR1C3在肝细胞癌...
A team of researchers has developed an ultrasound-based system that can non-invasively and remotely control genetic processes in live immune T cells so that they recognize and kill cancer cells.There ...
Individual tumors respond differently to cancer drugs, if at all. Until now, it remained a mystery why tumors have different reactions to the exact same therapy. But a new study at the USC Viterbi Sch...
A drug isolated from a marine pest holds promise for treating some of the world’s nastiest diseases, and researchers would love to find out just how effective it is – if only they could get their hand...
Headlines, of late, have touted the successes of targeted gene-based cancer therapies, such as immunotherapies, but, unfortunately, also their failures.Broad inadequacies in a widespread biological co...
One of the goals of personalized medicine is to be able to determine which treatment would work best by sequencing a patient’s genome. New research from the lab of Yimon Aye, assistant professor of ch...
“Your cancer has metastasized. I’m sorry,” is something no one wants to hear a doctor say.Cancer cells kill most often by crawling away from their original tumors to later re-root in vital parts of th...

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