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Using the mouse egg as a model system for the study of intracellular calcium signaling mechanisms
Oscillation eggs fertilization cell model system inositol
2014/12/11
Mouse metaphase II (MII)-stage eggs exhibit oscillatory Ca2+ responses ([Ca2+]i oscillations) following fertilization. The wealth of information regarding Ca2+ signaling pathways in eggs has allowed t...
The role of inositol 1,4,5 -trisphosphate receptor type-1 in regulation of intracellular calcium oscillations in mouse eggs
Calcium mammals fertilization eggs activation embryonic development cell cycle inositol receptor
2014/12/11
Calcium ([Ca2+]i) oscillations, a hallmark of mammalian fertilization, are essential to induce egg activation and embryonic development. As the zygotes transition through the cell cycle, these [Ca 2+]...