搜索结果: 1-10 共查到“理学 Amyloid”相关记录10条 . 查询时间(0.062 秒)
Formation and plasticity of glutamatergic synapses: Characterization of the roles of beta-amyloid precursor protein, scribble, and wingless at the Drosophila neuromuscular junction
Neurons circuit static core
2014/12/11
The flow of information through neuronal circuits relies on the ability of neurons to form synaptic connections with specific temporal and spatial properties. These properties are not static but have ...
Computational Potential Energy Minimization Studies on the Prion AGAAAAGA Amyloid Fibril Molecular Structures
Computational Potential Energy Minimization Amyloid Fibril Molecular Structures Biological Physics
2012/5/3
X-ray crystallography, NMR (Nuclear Magnetic Resonance) spectroscopy, and dual polarization interferometry, etc are indeed very powerful tools to determine the 3D structures of proteins (including the...
A novel canonical dual computational approach for prion AGAAAAGA amyloid fibril molecular modeling
Mathematical Canonical Duality Optimization Theory Two-body The-oretical Physics Structural Bioinformatics Technology
2011/10/9
Abstract: Many experimental studies have shown that the prion AGAAAAGA palindrome hydrophobic region (113-120) has amyloid fibril forming properties and plays an important role in prion diseases. Howe...
Atomic-resolution structures of prion AGAAAAGA amyloid fibrils
Amyloid Fibrils Prion AGAAAAGA Palindrome Atomic-resolution Structures
2011/8/31
To the best of the authors knowledge, there is little structural data available on the AGAAAAGA palindrome in the hydrophobic region (113-120) of prion proteins due to the unstable, noncrystalline and...
The Lennard-Jones Potential Minimization Problem for Prion AGAAAAGA Amyloid Fibril Molecular Modeling
Lennard-Jones Potential Minimization Problem, Lennard-Jones Potential Well, van der Waals radii
2011/9/13
The simplified Lennard-Jones (LJ) potential minimization problem is minimize f(x) = 4
N
Xi=1
N
X j=1,j
The Lennard-Jones Potential Minimization Problem for Prion AGAAAAGA Amyloid Fibril Molecular Modeling
Lennard-Jones Potential Minimization Problem Lennard-Jones Potential Well van der Waals radii
2011/7/26
The Lennard-Jones Potential Minimization Problem for Prion AGAAAAGA Amyloid Fibril Molecular Modeling.
Optimal atomic-resolution structures of prion AGAAAAGA amyloid fibrils
Optimal atomic-resolution structures prion AGAAAAGA amyloid fibrils
2011/1/5
To date, there is little structural data available on the AGAAAAGA palindrome in the hydrophobic region (113-120) of prion proteins, although many experimental studies have shown that this region has ...
A simplified exactly solvable model for beta-amyloid aggregation
simplified exactly solvable model beta-amyloid aggregation
2010/11/15
We propose an exactly solvable simplified statistical mechanical model for the thermodynamics of beta-amyloid aggregation, generalizing a well-studied model for protein folding. The monomer concentrat...
淫羊藿黄酮对APP转基因小鼠学习记忆及β-amyloid生成的影响
学习记忆 淫羊藿黄酮 β-amyloid
2010/8/31
淫羊藿黄酮对APP转基因小鼠学习记忆及β-amyloid生成的影响。
阿尔茨海默病中β淀粉样前体蛋白基因外显子9、10的mRNA表达及突变研究--Expression Variation and Mutation Analysis of Exon 9 and 10 in Amyloid Precursor Protein Gene in Alzheimer′s Disease
阿尔茨海默病 β淀粉样前体蛋白基因 表达 突变
2007/12/5
于上海地区汉人群中，探讨阿尔茨海默病(AD)患者外周血中β淀粉样前体蛋白基因外显子9、10（APP9~10）的mRNA表达水平，并作cDNA的点突变检测。采用半定量竞争性反转录聚合酶链反应(semi-quantitive competitive RT-PCR)技术测定APP9~10的mRNA表达水平；以聚合酶链反应（PCR）-限制性片段长度多态(RFLP)方法检测基因组DNA中载脂蛋白E基因(AP...