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Glycine protects cardiomyocytes against lethal reoxygenation injury by inhibiting mitochondrial permeability transition
reoxygenation permeability transition
2014/3/31
Post-ischaemic reperfusion may precipitate cardiomyocyte death upon correction of intra-cellular acidosis due in part to mitochondrial permeability transition. We investigated whether
glycine, an ami...
In 1976, Hunter and Haworth first characterized the mitochondrial permeability transition in beef heart mitochondria.
In 1987, Martin Crompton et al. implied that the pore is a unique molecular entit...
Preconditioning delays Ca 2+ -induced mitochondrial permeability transition
Preconditioning Calcium (cellular) Mitochondria Apoptosis Necrosis
2014/3/31
In protocol 1, New Zealand White rabbits underwent either no intervention (sham group) or 10 min of ischemia followed
by 5 min of reperfusion, preceded (PC) or not (C; control) by one episode of 5 mi...