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配子质量特别是卵子质量（卵质）是决定鱼类繁育成功和养殖效率的先决条件。鱼类的卵质由卵子中所储存的所有母源因子的集合所共同决定。开展母源因子对卵子发生和早期胚胎发育的调控研究可以指导鱼类卵质的评估，提升卵质，促进水产种业和养殖业的发展。在卵子发育和成熟的过程中，大量的母源mRNA被转录并囤积在卵子中，其在时空上有序的翻译激活或翻译抑制，即翻译控制（translational control），决定了...
Mapping Dynamic Histone Acetylation Patterns to Gene Expression in Nanog-depleted Murine Embryonic Stem Cells
Mapping Dynamic Histone Acetylation Patterns Gene Expression in Nanog-depleted Murine Embryonic Stem Cells
2010/11/15
Embryonic stem cells (ESC) have the potential to self-renew indefinitely and to differentiate into any of the three germ layers. The molecular mechanisms for self-renewal, maintenance of pluripotency ...