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Low serum ω-3 and ω-6 polyunsaturated fatty acids and other metabolites are associated with poor linear growth in young children from rural Malawi
arachidonic acid carnitine dehydroepiandrosterone docosahexaenoic acid malnutrition pregnenolone sulfate stunting
2018/11/21
Background: Stunting affects ～25% of children <5 y of age and is associated with impaired cognitive and motor development and increased morbidity and mortality. The pathogenesis of stunting is poorly ...
Placental vitamin D metabolism and its associations with circulating vitamin D metabolites in pregnant women
vitamin D pregnancy placenta trophoblasts vitamin D metabolism 25-hydroxyvitamin D megalin/cubilin CYP2R1 CYP27B1 CYP24A1
2018/11/21
Background: Little is known about placental vitamin D metabolism and its impact on maternal circulating vitamin D concentrations in humans.
Effects of dietary sodium on metabolites: the Dietary Approaches to Stop Hypertension (DASH)–Sodium Feeding Study
metabolomics epidemiology sodium intake trial high and low sodium intake feeding trial African American
2018/11/20
Background: High sodium intake is known to increase blood pressure and is difficult to measure in epidemiologic studies.
Circulating concentrations of biomarkers and metabolites related to vitamin status, one-carbon and the kynurenine pathways in US, Nordic, Asian, and Australian populations
biomarker Lung Cancer Cohort Consortium one-carbon metabolism tryptophan metabolism vitamin status
2018/11/14
Background: Circulating concentrations of biomarkers that are related to vitamin status vary by factors such as diet, fortification, and supplement use. Published biomarker concentrations have also be...
Choline and its metabolites are differently associated with cardiometabolic risk factors, history of cardiovascular disease, and MRI-documented cerebrovascular disease in older adults
cardiometabolic risk cerebrovascular disease choline older adults magnetic resonance imaging nutrition
2018/11/14
Background: There is a potential role of choline in cardiovascular and cerebrovascular disease through its involvement in lipid and one-carbon metabolism.
Vitamin D status of black and white Americans and changes in vitamin D metabolites after varied doses of vitamin D supplementation
vitamin D free vitamin D vitamin D-binding protein clinical trial African American white supplementation
2018/12/3
Background: Controversy exists over the disparate circulating 25-hydroxyvitamin D [25(OH)D] concentrations between black and white Americans.
Correlation Analysis of Secondary Metabolites and Environmental Factors in Tripterygium wilfordii
雷公藤红素 环境因子 回归分析 次生代谢
2009/11/18
采用多元逐步回归分析对分布于浙江、福建、湖南、湖北和贵州5个省内6类不同居群药用植物雷公藤(Tripterygium wi lfordi i)的160株个体进行了雷公藤红素含量和环境因子的相关性分析。结果表明, 在空间分布上, 各居群间的雷公藤红素含量差异较大, 其中湖南黄岩居群雷公藤红素含量最高, 为1.058 5×10-2g.g-1, 贵州雷山和福建泰宁居群最低,分别为4.988 9×10-3...