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Overexpression of a Hyperpolarization-Activated Cation Current (Ih) Channel Gene Modifies the Firing Activity of Identified Motor Neurons in a Small Neural Network
gene expression neuronal network
2015/8/25
Genetic network identification using convex programming
Gene the network capture gene cell material biological process
2015/8/7
Gene regulatory networks capture interactions between genes and other cell substances, resulting in various models for the fundamental biological process of transcription and translation. The expressi...
HAPPI: A Bioinformatics Database Platform Enabling Network Biology Studies
Database Genome Regulatory network
2015/5/26
The publication of the draft human genome consisting of 30,000 genes is merely the beginning of genome biology. A new way to understand the complexity and richness of molecular and cellular function o...
A Novel Network Biology Approach To Drug Target Selections
Network Biology Approach Drug Target Selections
2015/5/26
Conventional drug discovery focuses on single protein targets and follows a “sequence,
structure, and function” paradigm for selecting best protein targets to screen lead
chemical compounds. This es...
A sparse regulatory network of copy-number driven expression reveals putative breast cancer oncogenes
twork copy-number driven expression reveals putative breast cancer oncogenes
2010/11/15
The influence of DNA cis-regulatory elements on a gene's expression has been intensively studied. However, little is known about expressions driven by trans-acting DNA hotspots. DNA hotspots harboring...