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检测慢性肝病患者外周血凝血酶激活的纤溶抑制物活性(TAFI：A)水平，并探讨其与不同类型慢性肝损伤之间的相关性。方法 收集84例临床肝病患者和52例健康体检者的血液标本，采用发色底物法检测血浆TAFI：A，同时检测纤溶酶原活化物抑制剂(PAI-1)和组织型纤溶酶原激活物(t-PA)水平，并分析以上检测指标与不同类型慢性肝病间的相关性。结果 与健康对照组比较，病例组血浆TAFI：A水平均显著...
探讨靶向羧肽酶B2(CPB2)基因的小干扰RNA(siRNA)对乳腺癌MDA-MB-231细胞凝血酶激活的纤溶抑制物（TAFI）表达以及对乳腺癌细胞的生长和转移的影响。方法 将细胞分为siRNA-1组、siRNA-2组、siRNA-3组、阴性对照组和空白对照组5组，设计并化学合成编码TAFI基因（CPB2）的特异性siRNA，用脂质体2000转染至MDAMB-231细胞中，采用Weste...
The association of TAFI (Thrombin-activatable fibrinolysis inhibitor) with insulin resistance and components of metabolic syndrome in patients with metabolic syndrome
Metabolic syndrome TAFI insulin resistance
2010/12/21
To investigate the association of TAFI with components of metabolic syndrome and insulin resistance in patients with metabolic syndrome. Materials and methods: Patients between 20 and 70 years of age,...
The association of TAFI (Thrombin-activatable fibrinolysis inhibitor) with insulin resistance and components of metabolic syndrome in patients with metabolic syndrome
Metabolic syndrome TAFI insulin resistance
2010/11/22
To investigate the association of TAFI with components of metabolic syndrome and insulin resistance in patients with metabolic syndrome. Materials and methods: Patients between 20 and 70 years of age,...
TAFI基因编码区C291T的多态性与脑梗死的相关性研究
凝血酶激活的纤溶抑制物基因 单核苷酸多态性 脑梗死
2011/7/13
TAFI基因编码区C291T的多态性与脑梗死的相关性研究。