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Substituting whole grain for refined grain: what is needed to strengthen the scientific evidence for health outcomes?
grain health outcomes scientific evidence
2018/11/13
Worldwide, dietary guidelines have adopted the recommendation of consuming whole grain as part of a healthy diet. Ideally, dietary guidelines are based on convincing evidence, established by multiple ...
Whole-grain consumption and risk of coronary heart disease: results from the Nurses' Health Study
Diet whole grain refined grain
2016/6/1
Although current dietary guidelines for Americans
recommend increased intake of grain products to prevent coronary
heart disease (CHD), epidemiologic data relating wholegrain
intake to the risk of ...
Whole-grain wheat consumption reduces inflammation in a randomized controlled trial on overweight and obese subjects with unhealthy dietary and lifestyle behaviors: role of polyphenols bound to cereal dietary fiber
bioavailability ferulic acid inflammation obesity wholegrain wheat
2018/12/20
Background: Epidemiology associates whole-grain (WG) consumption with several health benefits. Mounting evidence suggests that WG wheat polyphenols play a role in mechanisms underlying health benefits...
The effects of a whole grain–enriched hypocaloric diet on cardiovascular disease risk factors in men and women with metabolic syndrome1,2,3
Whole-grain foods metabolic syndrome weight loss fiber
2009/4/20
Background: Whole-grain foods are associated in observational studies with a lower body mass index and lower cardiovascular disease (CVD) risk. However, few clinical trials have tested whether incorpo...
Dietary fiber and whole-grain consumption in relation to colorectal cancer in the NIH-AARP Diet and Health Study
Dietary fiber whole grain colorectal cancer fiber sources cohort study
2008/12/12
Background: Whether the intake of dietary fiber can protect against colorectal cancer is a long-standing question of considerable public health import, but the epidemiologic evidence has been inconsis...
Whole-grain consumption is associated with a reduced risk of noncardiovascular, noncancer death attributed to inflammatory diseases in the Iowa Women's Health Study 1,2,3,4
Whole-grain foods carbohydrate fiber inflammation
2008/12/9
Background: It has recently been shown that oxidative stress, infection, and inflammation are predominant pathophysiologic factors for several major diseases. Objective: We investigated the associatio...
Whole-grain intake and carotid artery atherosclerosis in a multiethnic cohort: the Insulin Resistance Atherosclerosis Study1,2,3
Atherosclerosis cereals diet ethnic groups cohort studies Doppler ultrasound
2008/12/9
Background: Whole-grain intake has been shown to be inversely associated with cardiovascular events, but an association with atherosclerosis is less well established. Objective: We sought to evaluate ...
Whole-grain rye and wheat foods and markers of bowel health in overweight middle-aged men
Wheat rye dietary fiber
2016/12/30
Three 4-wk interventions were undertaken in a randomized crossover design with 28 overweight men aged 40–65 y who had no history of bowel disease. Against a background intake of 14 g dietary fiber (DF...
Whole-grain and fiber intake and the incidence of type 2 diabetes
Diet grain whole grains
2016/12/29
Epidemiologic evidence of a preventive effect of whole grain against type 2 diabetes is mainly based on data from women. Information specific to men and women is needed.
Whole-grain foods, dietary fiber, and type 2 diabetes: searching for a kernel of truth
Whole-grain foods dietary fiber
2016/12/29
Tracing the historical development of a scientific concept is a difficult and often subjective exercise. In the field of dietary research, however, the possibility that something of physiologic import...
Whole-grain intake and insulin sensitivity: the Insulin Resistance Atherosclerosis Study
Whole grain diet nutrition
2017/1/4
Increased intake of whole-grain foods has been related to a reduced risk of developing diabetes and heart disease. One underlying pathway for this relation may be increased insulin sensitivity.
Associations of whole-grain, refined-grain, and fruit and vegetable consumption with risks of all-cause mortality and incident coronary artery disease and ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) Study
Whole grain fruit and vegetables all-cause mortality
2017/1/4
Recent epidemiologic study results showed that subjects who had high intakes of whole-grain foods had lower risks of death and heart disease than did subjects who had low intakes. However, the finding...
Whole-grain intake and the risk of type 2 diabetes:a prospective study in men
Type 2 diabetes whole grains refi ned grains men
2016/12/19
Background: Certain dietary components may play a role in the prevention of type 2 diabetes.Objective: We examined prospectively the associations between whole- and refined-grain intake and ...
Whole-grain intake is favorably associated with metabolic risk factors for type 2 diabetes and cardiovascular disease in the Framingham Offspring Study
Whole grains refi ned grains risk factors survey Framingham Offspring Study food-frequency questionnaire type 2 diabetes cardiovascular disease
2016/12/19
Background: The influence of whole grains on cardiovascular disease risk may be mediated through multiple pathways, eg, a reduction in blood lipids and blood pressure, an enhancement of insulin s...