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目的观察妊娠高血压疾病妇女血浆 Intermedin/Adrenomedullin-2(IMD/ADM2)水平变化，探讨IMD/ADM2在妊娠高血压疾病发病中的可能作用。方法妊娠高血压疾病患者40例（PIH组）；适龄未孕妇女20例（NG组）及正常妊娠妇女20例（PG组）分别采其静脉血；用放射免疫法测定血浆IMD/ ADM2水平。结果(1)血浆IMD/ ADM2水平PIH组、NG组、PG组分别为37...
Decreased Placental Adrenomedullin May Play Role in Preeclampsia
Preeclampsia adrenomedullin placental pathology
2009/6/30
Adrenomedullin (AdM) is a novel peptide that elicits a long-lasting vasorelaxant activity. It is expressed in several tissues, including adrenal medulla, heart, lung, kidneys, and cultured vascular sm...
Comparison of responses to adrenomedullin and calcitonin gene-related peptide in the feline erection model
ADM CGRP penile erection nitric oxide KATp channe
2009/2/17
The purpose of the present study was to investigate the effects of intracavernosal injections of adrenomedullin (ADM) and calcitonin gene-related peptide (CGRP), two structurally similar peptides,...
Adrenomedullin stimulates cyclic AMP production in the airway epithelial cells of guinea-pigs and in the human epithelial cell line
adrenomedullin airway cAMP epithelial cell guinea-pig human
2010/11/26
This study was designed to examine the effects of adrenomedullin (AM) on airway epithelial cells. Primary cultures of guinea-pig tracheal epithelial cells and the human bronchiolar epithelial cell lin...