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Correlation between the Prostaglandin D2/E2 Ratio in Nasal Polyps and the Recalcitrant Pathophysiology of Chronic Rhinosinusitis Associated with Bronchial Asthma
aspirin-intolerant asthma bronchial asthma chronic rhinosinusitis prostaglandin D2 prostaglandin E2
2010/11/17
The concentrations of PGD2 were significantly higher in the nasal polyps of the CRS-ATA group. The concentrations of PGE2 were lowest in the nasal polyps of the CRS-AIA group. The PGD2/PGE2 ratio was ...
Advances in the pathophysiology of bronchial asthma
apoptosis bronchial asthma eosinophils Fas ligand GATA-3 inflammation STAT6 T cells Th2 cytokines
2010/11/25
Asthma is a complex disorder associated with the activation of T lymphocytes and with eosinophil infiltration within the airways. A substantial amount of current research involves the interaction amon...
Improved Case of Bronchial Asthma by Re-administration of Pranlukast from Montelukast: Evaluation of Eosinophilic Inflammation in the Peripheral Airway
asthma eosinophil cationic protein (ECP) eotaxin induced sputum Pranlukast
2010/11/22
Following the re-administration of Pranlukast, the clinical symptoms disappeared within a few days and pulmonary function improved within 4 weeks. Eosinophils in the induced sputum almost completely d...
Identifying Predictors of Response to Suplatast Tosilate among Patients with Moderate to Severe Bronchial Asthma Receiving Inhaled Steroid Therapy
antiasthmatic agent basophil bronchial asthma eosinophil response prediction
2010/11/22
Twenty-two patients were assessed as responders according to our criteria. The percentage of blood eosinophil (%EOS, P = 0.015) and basophil (%BASO, P = 0.019) counts were identified as significant va...
Long-term Efficacy of House Dust Mite Immunotherapy in Bronchial Asthma: A 15-year Follow-up Study
allergy benefits bronchial asthma house dust mite immunotherapy
2010/11/22
Background: Specific immunotherapy for bronchial asthma has been documented to be efficacious in several studies; however, it is not known whether this efficacy is sustained for several years after ce...