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Alpha-Amanitin Poisoning, Nephrotoxicity and Oxidative Stress: An Experimental Mouse Model
Alpha-Amanitin Oxidative Stress Mycotoxins
2015/11/9
Background: Alpha-amanitin (α-AMA) plays a major role in Amanita phalloides poisoning, showing toxic effects on multi-organs, particularly on the liver and kidneys. Studies have shown a relationship b...
Histomorphometric changes in repaired mouse sciatic nerves are unaffected by the application of a scar-reducing agent
histomorphometry nerve regeneration nerve repair scarring sciatic nerve
2015/7/22
Microsurgical repair of transected peripheral nerves is compromised by the formation of scar tissue and the development of a neuroma, thereby limiting the success of regeneration. The aim of this stud...
In situ three-dimensional reconstruction of mouse heart sympathetic innervation by two-photon excitation fluorescence imaging
Microscopy Multi-photon Two-Photon TPLSM Confocal GFP Sympathetic Nervous System Cardiac Neuron Heart Cardiomyocyte
2015/5/21
The sympathetic nervous system strongly modulates the contractile and electrical function of the heart. The anatomical underpinnings that enable a spatially and temporally coordinated dissemination of...
NEUROPROTECTIVE STUDIES ON THE MPTP AND SOD1 MOUSE MODELS OF NEURODEGENERATIVE DISEASES
ALS MPTP SOD1 neurodegeneration
2015/5/21
The main, underlying cause of neurodegenerative disease is the progressive loss of neuronal structure or function, whereby central and/or peripheral nervous system circuitry is severely and irreversib...
TGF-β Signaling May Play a Role in the Development of Goblet Cell Hyperplasia in a Mouse Model of Allergic Rhinitis
allergic rhinitis epithelial cells Smad TGF-β
2010/11/12
In the mouse model of allergic rhinitis, OVA challenge induced phosphorylation of Smad2 predominantly in epithelial cells in the nasal mucosa. In addition, the administration of an inhibitor of TGF-β ...
Enzyme-Linked Immunosorbent Assays with High Sensitivity for Antigen-Specific and Total Murine IgE: A Useful Tool for the Study of Allergies in Mouse Models
allergen-specific IgE blocking reagent enzyme-linked immunosorbent assay
2010/11/16
Enhancer solutions are effective in improving ELISAs for total and antigen-specific murine IgE. Selection of blocking reagents was important to decrease unwanted enhancement of background signals and ...
Absence of Nasal Blockage in a Japanese Cedar Pollen-Induced Allergic Rhinitis Model Mouse
allergic rhinitis animal model cedar pollen nasal blockage sneezing
2010/11/16
The serum Cry j 1-specific IgE level showed clear elevation only in the group sensitized by Cry j 1 + Al(OH)3 and then challenged by Cry j 1. No elevations were seen in the groups sensitized by pollen...
An Improved Mouse Model of Atopic Dermatitis and Suppression of Skin Lesions by an Inhibitor of Tec Family Kinases
allergen atopic dermatitis mite Tec Th2
2010/11/18
We established a highly efficient, highly reproducible protocol to induce skin lesions in NC/Nga mice and successfully applied it to show the efficacy of terreic acid in treating skin lesions. This mo...
Effects of platelet activating factor on capacitation and acrosome reaction in mouse spermatozoa
2007/7/28
期刊信息
篇名
Effects of platelet activating factor on capacitation and acrosome reaction in mouse spermatozoa
语种
英文
撰写或编译
撰写
作者
Huo L J,Yang Z M
第一作者单位
刊物名称
Molecular Reproduction and Development
页面
2000,5...
Expression of leukemia inhibitory factor receptor and gp130 in mouse uterus during early pregnancy
2007/7/28
期刊信息
篇名
Expression of leukemia inhibitory factor receptor and gp130 in mouse uterus during early pregnancy
语种
英文
撰写或编译
撰写
作者
Ni H,Ding N Z,Harper M J K,Yang Z M
第一作者单位
刊物名称
Molecular Reproduction and
...
A Proposal Concept of a Polygene Network in Systemic Vasculitis: Lessons from MRL Mouse Models
autoantibody Cd72 collagen disease Fas genetic polymorphism
2010/11/18
In addition to the studies of cellular and molecular events in the pathogenesis of systemic vasculitis, a genome analysis of mouse models may shed some light on the complex clinicopathological manifes...
Attenuation of allergic airway inflammation and associated pulmonary functions by mycobacterial antigens is independent of IgE in a mouse model of asthma
airway hyperresponsiveness asthma Bacillus Calmette-Guérin eosinophils IgE Mycobacterium vaccae
2010/11/24
Neither BCG nor M. vaccae were able to attenuate the EAR, yet both were able to abrogate the parameters used to evaluate the LAR. Interestingly, in neither case were serum or OVA-specific IgE levels r...
Role of T cells in IgE-dependent triphasic cutaneous reaction caused by dinitrofluorobenzene in the mouse ear: Participation of CD8+ T cells
allergic dermatitis CD4+ T cell CD8+ T cell FK 506 IgE mice triphasic cutaneous reaction
2010/11/24
Whereas the magnitudes of IPR and LPR in BALB/c nu/nu T cell-deficient mice were similar to those in BALB/c +/+ mice, vLPR was not observed in nu/nu mice. In addition, FK 506 (3 and 5 mg/kg) and cyclo...
Effects of neuropeptides in the development of the atopic dermatitis of mouse models
atopic dermatitis calcitonin gene-related peptide neuropeptides olopatadine hydrochloride substance P
2010/11/22
It is suggested that repeated contact allergic dermatitis or mental stress may promote the development and exacerbation of AD and that substance P has a role in this response. In addition, it seems th...
Allergic Asthma: What Have We Learned from the Mouse Model?
allergy asthma interleukin-13 mast cell mouse T lymphocyte
2010/11/19
Despite advances and introduction of new and effective anti-asthma therapies, including inhaled corticosteroids and leukotriene modifiers, the mortality and morbidity of asthma is still a worldwide co...