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探讨类风湿性关节炎(RA)患者外周血单个核细胞(PBMC)中miR-99a的表达与辅助性T 细胞17(T helper cell 17,TH17)、调节性T细胞(regulatory cells, Treg)比率失衡的关系。方法?收集于我院就诊的RA患者80例，分为活动期RA组(42例)和稳定期RA组(38例)，以体检健康者42例作为健康人对照组。流式细胞术测定各组外周血PBMC中TH17、Tre...
Th17 Cells and Rheumatoid Arthritis -From the Standpoint of Osteoclast Differentiation-
IL-17 IL-23 osteoclast receptor activator of NF-κB ligand (RANKL) rheumatoid arthritis (RA) T cell Th17
2010/11/17
Rheumatoid arthritis is a chronic disease that affects multiple joints. It is considered to be an autoimmune disease in which a T helper (Th)-1 type response has been implicated to play an important p...