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Bisphosphonates Inhibit Expression of p63 by Oral Keratinocytes
osteonecrosis oral pathology keratinocytes
2014/11/6
Osteonecrosis of the jaw (ONJ), a side-effect of bisphosphonate therapy, is characterized by exposed bone that fails to heal within eight weeks. Healing time of oral epithelial wounds is decreased in ...
Megakaryocytes Regulate Expression of Pyk2 Isoforms and Caspase-mediated Cleavage of Actin in Osteoblasts
actin bone osteoblasts
2014/11/6
The proliferation and differentiation of osteoblast (OB) precursors are essential for elaborating the bone-forming activity of mature OBs. However, the mechanisms regulating OB proliferation and funct...
C-kit expression in the salivary gland neoplasms adenoid cystic carcinoma, polymorphous low-grade adenocarcinoma, and monomorphic adenoma
c-kit expression salivary gland neoplasms
2014/11/6
Objective. Differentiating between adenoid cystic carcinomas (ACCs), polymorphous low-grade adenocarcinomas (PLGAs), and the monomorphic adenomas (including canalicular adenomas, trabecular adenomas, ...
Assessment of p63 expression in the salivary gland neoplasms adenoid cystic carcinoma, polymorphous low-grade adenocarcinoma, and basal cell and canalicular adenomas
p63 adenoid cystic carcinoma
2014/11/6
Purpose The purpose of this study was to determine the extent of p63 immunoreactivity in the malignant salivary gland neoplasms adenoid cystic carcinoma (ACC) and polymorphous low-grade adenocarcinoma...
Expression of 5′-AMP-activated Protein Kinase with Starvation in Murine Thymocytes
AMP-activated protein kinase Thymocyte Glucocorticoid
2011/6/10
The 5′-AMP-activated protein kinase (AMPK) is a key enzyme in the protection of cells during energy crisis. AMPK is a heterotrimer consisting of a catalytic α (α1, 2) subunit and two regulatory subuni...
Evaluation of CD31 Expression and Mast Cell Count in Dysplastic Lesions and Squamous Cell Carcinoma of the Oral Cavity
SCC CD31 Mast cell Oral cavity
2015/9/21
Background: Squamous cell carcinoma (SCC) is the most common malignancy in the oral cavity. Angiogenesis is essential for development and progression of SCC. Recently, some studies have reported that ...
Evaluation of fibronectin,type I collagen and TGF-ß expression by human periodontal ligament fibroblasts exposed to root end filling materials
Evaluation fibronectin type collagen TGF-ß expression human periodontal ligament fibroblasts filling materials
2009/12/7
Background and Aim: Several materials have been introduced for retrograde fillings, pulp capping and sealing root perforations, but their biological effect on vital tissues and cells is not clear. The...
MMP-2, MMP-9,and iNOS Expression in Human Dental Pulp Subjected to Orthodontic Traction
Immunohistochemistry Dental pulp MMP-2 MMP-9 iNOS
2010/3/9
Objective: To test the hypothesis that some metalloproteinases (MMP-2, MMP-9) and inducible nitric oxide synthetase (iNOS) enzymes in dental pulp samples do not vary when subjected to orthodontic trea...
Trigeminal Expression of N-Methyl-D-Aspartate Receptor Subunit 1 and Behavior Responses to Experimental Tooth Movement in Rats
NMDA Receptor Experimental tooth movement Trigeminal ganglion Pain Face grooming
2010/3/8
Objective: To test the hypothesis that peripheral N-methyl-D-aspartate (NMDA) receptors play a role in pain induced by experimental tooth movement.
Materials and Methods: Male Sprague-Dawley rats wei...
Global Gene Expression Analyses of Mouse Fibroblast L929 Cells Exposed to IC50 MMA by DNA Microarray and Confirmation of Four Detoxification Genes' Expression by Real-time PCR
MMA cDNA microarray Gene expression
2009/9/14
Methyl methacrylate (MMA) is the main component of methyl methacrylic resin, which is widely used in dentistry. Previous studies have investigated whether MMA has any adverse effects on growth and gen...
Gene Expression of MC3T3-E1 Cells on Fibronectin-immobilized Titanium Using Tresyl Chloride Activation Technique
Osteoblasts Fibronectin-titanium GeneChip
2009/9/14
Fibronectin (FN) can be immobilized directly on titanium surfaces using tresyl chloride activation technique. The key advantage of tresyl chloride activation technique lies in its simplicity. In this ...
Gene expression monitoring in osteoblasts on titanium coated with fibronectin-derived peptide
Osteoblast RGD peptide GeneChip
2009/9/11
Enhanced adhesion and migration of osteoblastic cells on titanium (Ti) surface is believed to increase the success rate of implant therapy. A GRGDSP peptide derived from fibronectin was coated on Ti s...
Expression of IL-1β, MMP-9 and TIMP-1 on the Pressure Side of Gingiva under Orthodontic Loading
Pressure gingiva real-time RT-PCR IL-1β MMP-9 TIMP-1
2010/3/5
Objectives: To test the hypothesis that orthodontic pressure does not induce gene transcription of IL-1β, MMP-9, and TIMP-1 in pressure gingival soft tissue.
Materials and Methods: A total of 14 ma...
Functional Lateral Shift of the Mandible Effects on the Expression of ECM in Rat Temporomandibular Cartilage
Condylar cartilage Functional lateral shift of the mandible Extracellular matrix
2010/3/5
Objective: To test the hypothesis that the effects of mechanical stress from a functional lateral shift of the mandible have no effect on the expression of two main condylar cartilage extracellular ma...
Expression of Nitric Oxide Synthases in Orthodontic Tooth Movement
Nitric oxide synthase Force Osteocyte
2010/3/5
Objective: To investigate differential expression of NOS isoforms in periodontal ligament (PDL) and bone in tension and pressure sides using a rat model of orthodontic tooth movement (OTM).
Materia...