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Bioavailability of biotin given orally to humans in pharmacologic doses
Biotin biotin metabolites bioavailability
2016/5/30
Patients with carboxylase deficiency are treated
with pharmacologic doses of biotin.
Biotin bioavailability and estimated average requirement: why bother?
Biotin bioavailability
2016/5/30
Frank, symptomatic biotin deficiency probably occurs rarely.
The only well-documented cases have occurred in association
with total or near total intravenous feeding without biotin supplementation,
...
Indicators of marginal biotin deficiency and repletion in humans:validation of 3-hydroxyisovaleric acid excretion and a leucine challenge
Biotin leucine metabolism 3-hydroxyisovaleric acid bisnorbiotin egg whites
2016/12/19
Background: The results of clinical studies have provided evidence that marginal biotin deficiency is more common than was previously thought. A previous study of 10 subjects showed that the urin...
Marginal biotin deficiency during normal pregnancy
Pregnancy teratogenicity biotin deficiency 3-hydroxyisovaleric acid women
2016/12/17
Background: Biotin deficiency is teratogenic in several mammalian species. Approximately 50% of pregnant women have an abnormally increased urinary excretion of 3-hydroxyisovaleric acid (3-HIA), ...