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Efficacy and safety of vitamin D3 intake exceeding the lowest observed adverse effect level
Cholecalciferol calcidiol vitamin D3
2016/6/12
The Food and Nutrition Board of the National
Academy of Sciences states that 95 g vitamin D/d is the lowest
observed adverse effect level (LOAEL).
The skeletal benefits of calcium- and vitamin D3–fortified milk are sustained in older men after withdrawal of supplementation: an 18-mo follow-up study1,2,3
Milk supplementation fortified milk supplement withdrawal men bone mineral density
2009/4/20
Background: In a previous 2-y randomized controlled trial, we showed that calcium- and vitamin D3–fortified milk stopped or slowed bone loss at several clinically relevant skeletal sites in older me...
Safety of vitamin D3 in adults with multiple sclerosis
Vitamin D safety 25-hydroxyvitamin D 25(OH)D multiple sclerosis
2008/12/17
Background: Vitamin D3 may have therapeutic potential in several diseases, including multiple sclerosis. High doses of vitamin D3 may be required for therapeutic efficacy, and yet tolerability—in the ...
Randomized comparison of the effects of the vitamin D3 adequate intake versus 100 mcg (4000 IU) per day on biochemical responses and the wellbeing of patients
biochemical responses vitamin D3
2008/4/23
For adults, vitamin D intake of 100 mcg (4000 IU)/day is physiologic and safe. The adequate intake (AI) for older adults is 15 mcg (600 IU)/day, but there has been no report focusing on use of this do...
Relationships of low serum vitamin D3 with anthropometry and markers of the metabolic syndrome and diabetes in overweight and obesity
anthropometry vitamin D3
2008/4/23
Low serum 25 hydroxyvitamin D3 (vitamin D3) is known to perturb cellular function in many tissues, including the endocrine pancreas, which are involved in obesity and type II diabetes mellitus (TIIDM)...
25-Hydroxylation of vitamin D3: relation to circulating vitamin D3 under various input conditions
Vitamin D vitamin D3
2016/12/30
Neither the efficiency of the 25-hydroxylation of vitamin D nor the steady state relation between vitamin D3 and 25-hydroxyvitamin D [25(OH)D] has been studied in humans.