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Study:Changing the environment within bone marrow alters blood cell development
Changing the environment bone marrow blood cell development
2017/3/14
Researchers at the University of Illinois report they can alter blood cell development through the use of biomaterials designed to mimic characteristics of the bone marrow.The findings, reported in th...
CIS REGULATORY MODULE DISCOVERY IN TH1 CELL DEVELOPMENT
TH1 cell development STAT4 ChIP-on-chip ChIP-Seq
2015/5/26
Immune response enables the body to resist foreign invasions. The Inflammatory response is an important aspect in the immune response which is articulated by elements such as cytokines, APC, T-cell an...
DIFFERENTIAL ROLE OF PI-3KINASE p85 (α & β) REGULATORY SUBUNITS IN MAST CELL DEVELOPMENT
Cell cycle -- Regulation Enzymes
2015/5/25
Stem cell factor (SCF) mediated c-Kit signaling, and downstream activation of Phosphatidylinositol-3 Kinase (PI-3K) is critical for multiple biological effects mediated by mast cells. Mast cells expre...
B cell development and immunoglobulin genes in cattle
Cellular immune globulin genes immune system lymphoid tissue immunoglobulin molecules
2014/12/11
The objective of this dissertation was to study B cell development and the mechanism of immunoglobulin gene diversification in cattle. The bovine immune system differs from that of the mouse and human...
Studies of bovine B cell development
B cells cells animals old animals spleen gene rearrangement
2014/12/11
This dissertation was to study the sites of B cell development, the mechanisms of Ig diversification, the time when diversification occurs, the B cell repertoire during development and usage of Ig lig...
Using new single-cell technologies, researchers create comprehensive map of human B cell development
new single-cell technologies researchers create comprehensive map human B cell development
2014/5/13
In a new paper published in the journal Cell, a team of researchers led by Dana Pe’er at Columbia University and Garry Nolan at Stanford University describes a powerful new method for mapping cellular...
Using new single-cell technologies, researchers create comprehensive map of human B cell development
new single-cell technologies researchers create comprehensive
2014/4/28
Researchers have described a powerful new method for mapping cellular development at the single cell level. This method will greatly improve researchers' ability to investigate development in cells of...
Assessment of Piwil2 Gene Expression Pattern upon Germ Cell Development from Mouse Embryonic Stem Cell
Embryonic stem cell Germ cell Embryoid body Piwil2
2015/9/18
Background: In order to improve culture conditions for optimal spermatogenesis, quantitative assessment of the male germ cell gene expression profile upon spontaneous ES cell differentiation is necess...
Impaired germ cell development in the testes of immature rats with neonatal hypothyroidism
Gonocyte Sertoli cell thyroid hormone stereology optical disector germ cell number
2009/2/17
The induction of neonatal hypothyroidism from day 1 to day 25 postpartum using 6-propyl-2-thiouracil (PTU) resulted in a 45% and 77% reduction of testis weight on days 20 and 30, respectively, and a...
Genetic and cellular analysis of male germ cell development
Primordial germ cell gonocyte testis growth factor
2008/12/25
The evolution of the germline has been studied for many decades. Although the pathway of germ cell primordial migration and the kinetic evolution of the gonocytes are well known, their genetic and...
Suplatast Tosilate Inhibits Human Mast Cell Development from Cord Blood Progenitors
cord blood progenitors human mast cells stem cell factor suplatast tosilate
2010/11/19
Background: Localized mast cell accumulation has been reported in a number of human diseases. Suplatast tosilate has been reported to inhibit IL-3-dependent murine mast cell development, and therefore...