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大鼠正糖钳实验方法学
葡糖钳技术 正糖钳 医学实验技术 胰岛素
2010/1/8
目的:建立大鼠正糖钳实验技术。方法:用回归分析和相对标准偏差评价血糖仪的可行性;采用706代血浆作为载体溶液配制胰岛素输注液;改变胰岛素输注速率或葡萄糖输注速率,观察血糖的变化速率。结果:血糖仪相关性好,且精密度高,可满足实验要求;用706代血浆配制胰岛素输注液可满足实验要求;稳态血糖可控制在基础血糖±0.2 mmol.L-1; 血糖对葡萄糖输注速率比对胰岛素输注速率更敏感。结论:首次在国内成功建...
本文报告用小剂量链脲霉素(25 mg/kg)给雌性大鼠静脉注射,使大鼠糖耐量异常,然后加喂高热量食物,引起动物肥胖,饲养8或18周,可形成类似Ⅱ型糖尿病的肥胖大鼠模型。
Stereological analysis of renal glomeruli following chronic lead intoxication in rat during a continuos period of 8 weeks
renal glomeruli chronic lead intoxication rat
2010/1/6
Background: Stereologic methods are used to obtain quantitative information about three dimensional structures from histologic sections. The aim of present study was using new and unbiased stereologic...
The ulcerogenic effect of Indomethacin in diabetic rats
Diabetic rats Gastric ulcer Streptozocin
2010/1/6
We have studied the ulcerogenic effect of indomethacin in stretozocin. Induced diabetic rats. Streptozocin (65 mg kg-1) was injected intraperitoneally to male wistar rats. The blood glucose concentrat...
The effects of Quinpirole and Sulpiride on conflict responses in rat
Quinpirole Sulpiride conflict responses rat
2010/1/6
In this investigation wer studied the effect of dopaminergic system on the conflict behavior in rat, using vogel’s test. The related drugs were injected intraperitonealy (IP), and produced the followi...
STUDY OF CORRELATION BETWEEN SYSTOLIC BLOOD PRESSURE AND ANGIOTENSIN CONVERTING ENZYME (ACE) ACTIVITY IN STZ INDUCED DIABETIC RATS
STZ induced diabetic rats Diabetes mellitus morbidity mortality
2010/1/6
Background: Diabetes mellitus is a worldwide health problem affecting 1-2% of the population. It is responsible for numerous morbidity and mortality consequences due to vascular events such as hyperte...
脉冲电磁场对大鼠骨骼肌急性挫伤后触诱发痛的影响
骨骼肌 挫伤 疼痛 脉冲电磁场
2012/7/6
目的观察脉冲电磁场(PEMFs)对大鼠骨骼肌急性挫伤后行为学及机械刺激缩足反射阈值(PWMT)的影响,并探讨PEMFs在大鼠骨骼肌急性挫伤早期治疗中的应用。 方法将42只SD大鼠分为PEMFs组、造模对照组和空白对照组,每组14只。PEMFs组和造模对照组采用重物自由落体打击法建立大鼠骨骼肌急性挫伤模型,空白对照组不做任何处理。造模成功后,PEMFs组即刻予以PEMFs干预,频率14 Hz,频率可...
The effect of Lead Acetate on the Nitric Oxide system in the rat Hippocampal cells:An in-vitro study
Pyramidal cell Chronic toxicity Rat hippocampal cells
2010/1/5
The mechanism by which lead may cause a perturbotion in the nevous system is through the nitric oxide synthase. In this study the effect of lead acetate on the hippocampal constitutive nitric oxide pr...
Sex affects the feeling of pain in the mice,possible involvement of nitric oxide
Pain nitric oxide mice
2010/1/5
It has been shown that nitric oxide is a mediator with a major role in pain signaling at the level of dorsal root ganglion neurons of the spinal cord. The main objective of the present study was to el...
Effect of Cryptococcal Capsular Compounds on Blood Coagulation in Animal Models
Glucoronoxylomannan (GXM) Cryptococcus neoformans Blood Coagulation
2010/1/5
Glucoronoxylomannan (GXM) is the most important compound of polysaccharide capsule in Cryptococcus neoformans that causes infection in its recognition as a foreign agent by immune system. Because of i...
Distribution of I-125-IgG in normal and induced inflammation in mice
Distribution I-125-IgG inflammation mice
2009/12/31
Antibodies are a diverse class of glycoproteins that specially bind with antigen and elicit a number of secondary responses in vivo. Most of the applications of antibodies in basic research diagnosis ...
Correlation of the intraocular pressure with increased intracranial pressure in rabbits
Intracranial pressure intracranial pressure rabbits
2009/12/30
Although measurement of intracranial pressure by noninvasive methods has been suggested, but mainly invasive methods are used for this purpose-Increase in episcleral venous pressure can be expected to...
PRELIMINARY RODENT CONTROL PROGRAM IN BANDAR ABBAS,SOUTHERN IRAN
Rodent Control Zincphosphid Comatetralil
2009/12/30
A general rodent control program was carried out in Bandar Abbas in the Persian Gulf (15 Sep-22 Oct 1984). Researches on the variety of the rodents and their parasites were done and Zincphosphide and ...
DIGESTIBILITY OF LEGUMES 1:EFFECT OF REANS ON ORGANS
Legumes Digestibility of nitrogen rats
2009/12/30
While legumes are regarded as good sources of protein they may be poorly digested, so it is useful to determine their digestibility which would give a desirable objective in a breeding programme. In t...