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铜绿假单胞菌和大肠杆菌是医院和兽医临床上常见的病原菌,容易造成人类和动物感染,给疾病治疗和经济发展带来极大的挑战。为了开发出靶向铜绿假单胞菌和大肠杆菌黏肽合成酶(PBPs)的新型先导化合物,笔者以铜绿假单胞菌PBP3和大肠杆菌PBP1b、PBP4、PBP5作为靶点,针对ZINC数据库,使用分子对接软件DOCK6.5进行了虚拟筛选。之后,根据得分情况和结构分析,找出了具有全新结构的先导化合物,进行了...
In this study, we evaluated the phylogenetic diversity of the cecal microbiota of 3-week-old ducklings fed three diets differing in metabolizable energy. The contents of the ceca were collected from ...
The study evaluated the rumen fermentation pattern, microbial population, fatty acid composition, and antioxidant status in the rumen fluid and blood of sheep in response to a diet supplemented with h...
Here, the ability of Pediococcus pentosaceus and Pediococcus acidilactici to utilise potato tuber juice for cell synthesis without an external nutrient supplement was investigated, and the influence o...
Shiga toxin-producing Escherichia coli (STEC) O157:H7 is an important foodborne pathogen worldwide. In Turkey, little is known about the molecular characteristics of STEC O157:H7 isolates. The aim of ...
Apparent total tract digestibility (ATTD), apparent ileal digestibility (AID) and standardised ileal digestibility (SID) of dry matter, nitrogen, energy and amino acids were evaluated in six weanling ...
The direct fluorescence microscopy method with ethidium bromide staining can be used for somatic cell counting in raw cow’s milk. However, this method has some limitations that may influence the resul...
The purpose of this study was to comparatively assess the antidermatophyte and antioxidant activities of enilconazole, Nigella sativa (NS) and enilconazole with NS in the treatment of dermatophytosis ...
The aim of this experiment was to test the hypothesis that conjugated linoleic acid (CLA) in diets of finishing pigs fed linseed can improve the quality and oxidative stability of meat and subcutaneou...
Studies on the frozen storage of human blood products have benefited veterinary transfusion medicine in recent years, but the long-term cryopreservation of canine red blood cells (RBCs) has not yet be...
This study was conducted to evaluate the occurrence of the genus Arcobacter in cats and dogs in the Czech Republic. These animals may be carriers of the bacteria and potential sources of human infecti...
The aim of this study was to assess the cost-effectiveness of a fermented liquid feeding and enzyme supplementation of dry fodders containing rye grain for pig fattening. Two experiments were performe...
The aim of this study was to use high throughput sequencing of piglet faeces to investigate if the favourable effects of sodium humate (HNa) and zinc oxide (ZnO) in post-weaning diarrhoea (PWD) treatm...
The goal of this work was to understand how polymorphonuclear leukocytes (PMN), the first line of cellular defence, integrate and prioritize multiple chemotactic signals to navigate during periods of ...

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