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Effect of Am-80, a novel retinoid derivative, on contact hypersensitivity caused by repeated applications of hapten in mice
2, 4-dinitrofluorobenzene Am-80 contact dermatitis cytokine retinoid
2010/11/25
Some retinoids show an anti-inflammatory action through regulation of transcription of various genes. In the present study, the inhibitory effect of 4-((5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphth...
Suppressive effects of the Chinese herbal remedy Tripterygium wilfordii Hook f on eosinophilia and IgE hyperproduction in mice
eosinophilia immunoglobulin E Mesocestoides cortii mouse suppression Tripterygium wilfordii
2010/11/25
The effects of chloroform extract of Tripterygium wilfordii Hook f (TWH extract) on eosinophilia and IgE hyperproduction induced by Mesocestoides cortii infection were examined in BALB/c mice. Mice we...
Psychosocial stress enhances IgE-mediated triphasic cutaneous reaction in mice: Antagonism by Yokukan-san (a Kampo medicine) and diazepam
atopic dermatitis diazepam IgE-mediated skin reaction Kampo medicine psychosocial stress social isolation stress Yokukan-san
2010/11/25
The results of the present study indicate that IgE-mediated triphasic cutaneous reactions were exacerbated by social isolation stress and suggest that Yokukan-san and diazepam antagonize isolation str...
Passive anaphylaxis and IgE antibody production are compromised in tumor necrosis factor- and in granulocyte-macrophage colony stimulating factor-deficient mice
granulocyte-macrophage colony stimulating factor-deficient mice IgE mast cell passive cutaneous anaphylactic reaction tumor necrosis factor-deficient mice
2010/11/25
Background: A number of recent studies has demonstrated a critical role for mast cells and mast cell-derived cytokines, especially tumour necrosis factor (TNF), in the control of host defense mechanis...
Effect of repeated antigen inhalation on airway inflammation and bronchial responsiveness to acetylcholine in interleukin-5 transgenic mice
bronchial hyperresponsiveness eosinophils interleukin-5 mice
2010/11/25
Bronchial hyperresponsiveness (BHR) is a characteristic feature of bronchial asthma, yet its precise mechanism remains obscure. Human studies have demonstrated that T helper 2 cytokines, including int...
EFFECTS OF VITEX AGNUS CASTUS ON MICE FETUS DEVELOPMENT
Vitex agnus castus Mice fetus development
2010/4/20
Vitex agnus castus (chasteberry) is a popular treatment for the management of female reproductive disorders including corpus luteum insufficiency, premenstrual syndrome (PMS), menopausal symptoms, and...
The effects of genistein, a tyrosine kinase inhibitor on acute and chronic inflammation in diabetic mice
Diabetes Genistein Inflammation Mice Streptozotocin Tyrosine kinase
2010/2/3
The effects of tyrosine kinases on acute and chronic inflammation during diabetes are not fully determined. Therefore, the present study focuses on the effects of genistein, a tyrosine kinase inhibito...
Effects of ultraviolet-inactivated herpes simplex virus type I on atopic dermatitis-like lesions in NC/Nga mice: Role of the suppressor of cytokine signaling in the skin
atopic dermatitis herpes simplex virus suppressor of cytokine signaling (SOCS) Th1 Th2
2010/11/22
Ultraviolet-inactivated HSV treatment would appear to induce a Th1 cellular response and downregulate that of the Th2 pathway in AD-like lesions of NC/Nga mice by bringing about a reduction of SOCS3 e...
Contribution of CD4+ or CD8+ T cell subsets in the induction of asthma in C57BL/6 mice
asthma C57BL 6 mice CD4+ T cell CD8+ T cell influenza virus
2010/11/22
Background: Respiratory viral infections are known to be a risk factor for the exacerbation of asthma. In a model of asthma with influenza A virus infection, dendritic cells play an important role dur...
Scratching behavior in NC/Nga mice with dermatitis: Involvement of histamine-induced itching
atopic dermatitis histamine itching NC Nga mice scratching
2010/11/24
We found two types of scratching behavior in NC mice, one of a short duration (0.3-1.0 s) and the other of a longer duration (over 1.0 s). The number of short scratchings and HDC activity increased wi...
Reduced Serum Antibody Production and Acute Airway Inflammation in Interleukin 6-deficient Mice Challenged with Ovalbumin
animal asthma cytokine eosinophil IL-6
2010/11/19
Background: IL-6 is a unique cytokine that has pro- and anti-inflammatory property. The purpose of this study was to clarify the role of IL-6 in the allergic airway inflammation.
Methods: We challeng...
Effect of Storage on the Infectivity of Vampirolepis Nana var. Nana Eggs to Swiss Albino Mice
Vampirolepis nana Cestode Swiss albino mice
2010/2/3
Vampirolepis nana is the most common cestode in humans especially children. Domestic mice and rats can serve as definitive hosts for V. nana. Confusion exists over the species status and host-specific...
Induction of Experimental Allergic Encephalomyelitis in C57/BL6 Mice:An Animal Model for Multiple Sclerosis
Experimental allergic encephalomyelitis C57/BL6 mice Multiple sclerosis Myelin oligodendrocyte glycoprotein
2010/2/8
Basic research on the autoimmune disease multiple sclerosis has been performed mainly on its animal model namely experimental allergic encephalomyelitis. There are many different approaches establishe...
The Effect of Vitamin E on Splenocytes Apoptosis of Gamma-Irradiated BALB/c Mice
Apoptosis Free Radicals Gamma Radiation Vitamin E
2010/2/8
Apoptosis, a physiologic mechanism to eliminate unwanted cells, is also induced by ionizing irradiation, through production of free radicals. It has been demonstrated that antioxidants such as vitamin...
The Role of Overproduction of Nitric Oxide in Apoptosis of BALB/C Mice Macrophages Infected with LeishmaniaMajor in Vitro
Nitric Oxide Apoptosis BALB/C Mice Macrophages LeishmaniaMajor
2010/4/26
Nitric oxide (NO) derived from activated macrophages has been shown to be crucial for the host's leishmanicidal activities. Excess NO, however, can in¬duce apoptosis in some cell types, including ...