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Background: Whole-grain foods are associated in observational studies with a lower body mass index and lower cardiovascular disease (CVD) risk. However, few clinical trials have tested whether incorpo...
Background: Several investigators have concluded that the waist-to-height ratio is more strongly associated with cardiovascular disease risk factors than is the body mass index (BMI; in kg/m2).Objecti...
Background: Regular exercise and consuming long-chain n–3 fatty acids (FAs) from fish or fish oil can independently improve cardiovascular and metabolic health, but combining these lifestyle modificat...
Background:The magnitude of the effect of soy protein on lipoprotein concentrations is variable. This discordance is likely attributable to the various forms of soy protein used and to unrecognized sh...
In evaluating the cardiovascular merits of n–3 fatty acids, Wang et al (1) appropriately sought the best available evidence and used randomized controlled human trials (RCTs) as their benchmark. As th...
Background: Lowering the dietary glycemic load and increasing protein intake may be advantageous for weight management. Objective: This randomized controlled trial was designed to evaluate the effects...
The aim of this one-year study was to examine whether greater weight loss could be achieved and sustained with a GMP-enriched whey powder supplement compared with a skim milk powder supplement.
The role of body iron stores in free radical–induced peroxidation and cardiovascular disease risk has been debated, but controlled feeding studies using measurements of non-transferrin-bound iron (NTB...
Soluble-fiber β-glucan derived from oats can reduce cardiovascular disease (CVD) risk through reductions in total and LDL cholesterol. Barley-derived β-glucan may also improve serum cholesterol, but l...
Background: Tocotrienols have been reported to lower LDL-cholesterol and fasting glucose concentrations and to have potent antioxidant effects, but the results are contradictory.Objective: T...
Background: The short-chain fatty acids formed in the human colon by the bacterial fermentation of fiber may have an antiinflammatory effect, may reduce insulin production, and may improve lipid ...
Background: The increasing proportion of iron-replete individuals in industrialized countries and the possible increased risk of cardiovascular disease (CVD) among men with high iron stores raise...
Background: An elevated plasma total homocysteine (tHcy) concentration seems to increase the risk of cardiovascular disease.Objective: We evaluated the determinants of tHcy in healthy French...
Background: Canadian native populations, which traditionally consume large amounts of fish, have lower rates of mortality from heart disease than do Canadian nonnative populations, which have low...
In this issue of the Journal, Anderson et al (1) report their metaanalysis of 8 studies that compared the effects on serum lipids of consumption of the viscous soluble fiber psyllium with those of a...

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