搜索结果: 16-30 共查到“医学 receptor”相关记录191条 . 查询时间(0.108 秒)
Activation of APE1/Ref-1 is dependent on reactive oxygen species generated after purinergic receptor stimulation by ATP
APE1 Ref-1
2014/12/12
Apurinic apyrimidinic endonuclease redox effector factor-1 (APE1/Ref-1) is involved both in the base excision repair (BER) of DNA lesions and in the eukaryotic transcriptional regulation. APE1/Ref-1 i...
The phosphoinositide-binding protein p40phox activates the NADPH oxidase during FcγIIA receptor–induced phagocytosis
NADPH oxidase phagocytosis
2014/12/12
Superoxide produced by the phagocyte reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase is essential for host defense. Enzyme activation requires translocation of p67phox, p47phox, an...
Soluble toll like receptor 2 (TLR-2) is increased in saliva of children with dental caries
saliva Soluble toll like receptor 2 dental caries
2014/11/6
Background Dental caries is the most common microbial disease affecting mankind. Caries risk assessment methods, identification of biomarkers and vaccine development strategies are being emphasized to...
Serum Lectin-Like Oxidized-Low Density Lipoprotein Receptor-1 and Adiponectin Levels Are Associated With Coronary Artery Disease Accompanied With Metabolic Syndrome
LOX-1 Coronary Artery Disease Adiponectin Metabolic Syndrome
2015/10/14
Background: Coronary artery disease (CAD) is a major public health problem for developed and developing countries and is the single leading cause of death worldwide.
Effect of Breastfeeding on Serum Osteoprotegerin and Soluble Receptor Activator of Nuclear Factor-Kappa B Ligand in Full Term Neonates
Breast Feeding Infant Formula Osteoprotegerin sRANKL Tumor Necrosis Factor-Alpha (TNFα)
2015/10/9
Background: Human breast milk, the sole source of nutrition during the early neonatal period, is rich in nutrients, hormones, growth factors, and immunoactive molecules, which influence the growth, de...
Accuracy of Estrogen and Progesterone Receptor Assessment in Core Needle Biopsy Specimens of Breast Cancer
Breast Neoplasm Carcinoma Estrogen Progesterone
2015/9/30
Background: Diagnosis of breast cancer is completed through core needle biopsy (CNB) of the tumors but there is controversy on the accuracy of hormone receptor results on CNB specimens.
Use of a Three-Dimensional Virtual Environment to Teach Drug-Receptor Interactions
3-dimensional virtual reality drug-receptor interactions pharmacology
2018/6/14
Objective. To determine whether using 3-dimensional (3D) technology to teach pharmacy students about the molecular basis of the interactions between drugs and their targets is more effective than trad...
Transcriptional Expression Profile of Toll Like Receptor 1 - 10 mRNA in Bovine Peripheral Mononuclear Cells in Response to Foot and Mouth Disease Antigens
Innate Immunity FMDV DNA Vaccine TLR Genes
2013/1/28
Toll like receptors are the primary component of innate immune response. The comparison of expression of innate immune genes TLR 1 - 10 was carried out by real time PCR by quantifying mRNA in bovine P...
Tyrosine kinase receptor B isoforms alter APP and BACE1 endogenous levels independently of BDNF
TrkB Alzheimer BACE1 SHC NFAT
2013/1/28
Brain derived neurotrophic factor (BDNF) levels and signaling via the tyrosine receptor kinase B (TrkB) have been shown to be altered in Alzheimer’s Disease. In addition, it has been reported that the...
Is Chemokine Receptor CCR9 Required for Synovitis in Rheumatoid Arthritis? Deficiency of CCR9 in a Murine Model of Antigen-Induced Arthritis
Chemokine Receptor CCR9 Rheumatoid Arthritis Inflammation Antigen-Induced Arthritis Mouse Mod-el Monocytes/Macrophages
2013/1/31
Objectives: Monocytes/macrophages accumulate in the synovial membrane in rheumatoid arthritis and play a key role in disease pathogenesis, contributing to inflammation, cartilage destruction and bone ...
5-HT2A Receptor Activation Normalizes Exaggerated Fear Behavior in p-Chlorophenylalanine (PCPA)-Treated Rats
Fear Conditioning Startle Reflex 5-HT2 DOI Ketanserin SB 206553
2013/1/29
Deficits in serotonin (5-hydroxytryptamine, 5-HT) neurotransmission are implicated in abnormal emotional behaviors such as aggression, anxiety, and depression. However, the specific 5-HT receptor mech...
Is Chemokine Receptor CCR9 Required for Synovitis in Rheumatoid Arthritis? Deficiency of CCR9 in a Murine Model of Antigen-Induced Arthritis
Chemokine Receptor CCR9 Rheumatoid Arthritis
2013/1/31
Objectives: Monocytes/macrophages accumulate in the synovial membrane in rheumatoid arthritis and play a key role in disease pathogenesis, contributing to inflammation, cartilage destruction and bone ...
Is Chemokine Receptor CCR9 Required for Synovitis in Rheumatoid Arthritis? Deficiency of CCR9 in a Murine Model of Antigen-Induced Arthritis
Chemokine Receptor CCR9 Rheumatoid Arthritis Inflammation Antigen-Induced Arthritis Mouse Mod-el Monocytes/Macrophages
2013/9/2
Objectives: Monocytes/macrophages accumulate in the synovial membrane in rheumatoid arthritis and play a key role in disease pathogenesis, contributing to inflammation, cartilage destruction and bone ...
Decreased serum level of soluble-leptin-receptor in patients with systemic lupus erythematosus
Soluble-leptin-receptor Autoantibody Systemic lupus erythematosus Depression
2015/9/28
Background: There is some evidence suggesting that leptin and its negative regulator, soluble-leptinreceptor (SLR) may be able to influence inflammatory and autoimmune processes.
Microinjection of NMDA-type glutamate receptor agonist NMDA and antagonist D-AP-5 into the central nucleus of the amygdale alters water intake rather than food intake
NMDA受体 NMDA D-AP-5 杏仁中央核 食物摄取 水摄取
2012/6/28
目的探讨杏仁中央核中的N-甲基-D-天冬氨酸（NMDA）型谷氨酸受体对食物和水摄取的影响。方法不锈钢套管植入雄性Sprague-Dawley大鼠一侧杏仁中央核内，NMDA型谷氨酸受体激动剂原型物NMDA，或选择性NMDA受体拮抗剂D(?)-2-氨基-5-磷酰基戊酸（D-AP-5）微量注射入饱食和含水度正常的大鼠的杏仁中央核内。结果杏仁中央核内注射入8.50，17.00，或34.00 nmol NM...