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Age-related increases in basement membrane thickness have been noted in many tissues, including the testis. The current investigation examined the morphology of the basement membrane in the aged B...
Gene expression in the aging brown Norway rat epididymis
Gene expression aging brown Norway rat epididymis
2009/2/13
The mammalian epididymis is the site where spermatozoa are matured and then stored. Though many studies have described epididymal functions and their regulation, little is known about how aging af...
Testicular steroidogenesis in the aging brown Norway rat
Aging testis steroidogenesis Leydig cell rat
2009/2/12
In seeking an animal model of age-associated changes in the male reproductive tract, we examined the effects of age on the health and testicular steroidogenic activity of the Brown Norway rat, with ...
The effect of aging on the seminiferous epithelium of the brown Norway rat
seminiferous epithelium brown Norway rat
2009/2/12
Aging of the mammalian testis is often accompanied by loss of germ cells and, as a result, decreased daily sperm production. It is currently unknown whether cell loss is the result of aging-related ch...
The effects of normal aging on the response of the pituitary-gonadal axis to chronic clomiphene administration in men
Testes inhibin gonadotropins age
2009/2/7
Serum androgens decline with age in normal men, despite normal or elevated bioactive serum gonadotropins, suggesting that primary testicular dysfunction occurs with aging. The authors further assess...
Influences of aging changes in proliferative rate of PDL cells during experimental tooth movement in rats
Aging Tooth movement Periodontal ligament Bromodeoxyuridine Immunohistochemistry
2009/1/8
This study was designed to investigate the influences of aging changes in the proliferative activity of PDL cells during experimental tooth movement in rats. Young (6-week-old) and adult (14-week-ol...
Effects of Aging on Mouse Tongue Epithelium Focusing on Cell Proliferation Rate and Morphological Aspects
Aging Morphology Proliferative activity
2010/12/1
The aim of this study was to investigate cell proliferation rate and certain morphological features of mouse epithelium as aging progresses. Tongue biopsies were performed on female mice (Mus domestic...
Sperm structural and motility changes during aging in the Brown Norway rat
Sperm structural motility changes Brown Norway rat
2008/12/26
The Brown Norway rat provides a useful model to study aging of the male reproductive tract because of the selective age-dependent pathological changes that are found in the testis, epididymis, and pro...
Leydig cell aging：steroidogenic acute regulatory protein（StAR）and cholesterol side-chain cleavage enzyme
Leydig cell aging protein（StAR） cholesterol side-chain cleavage enzyme
2008/12/26
Primary points of control in steroidogenesis are the transport of cholesterol from intracellular stores to the inner mitochondrial membrane, and the subsequent conversion of cholesterol to pregnenolon...
In Vivo Aging of Orthodontic Alloys：Implications for Corrosion Potential, Nickel Release, and Biocompatibility
Nickel Nickel release Corrosion potential Orthodontic alloy Biocompatibility
2008/12/26
Despite the large number of studies investigating nickel release from orthodontic stainless steel and nickel-titanium alloys, there is a lack of conclusive evidence with respect to the composition a...
Aging does not impair the anabolic response to a protein-rich meal
Nutrition stable isotopes sarcopenia diet beef amino acids
2008/12/25
Background: Sarcopenia is a debilitating condition afflicting the elderly that may be facilitated by insufficient or ineffectual intake of dietary protein. We previously showed that free-form essentia...
Spontaneous hyperplasia of the ventral lobe of the prostate in aging genetically hypertensive rats
Spontaneous hyperplasia ventral lobe prostate aging genetically hypertensive rats
2008/12/25
Recent studies have shown that the prostatic autonomic innervation takes part in its homeostasis and growth. Other works showed that spontaneously hypertensive rats (SHR) show excessive sympathetic ...
Spermatozoa Have Decreased Antioxidant Enzymatic Capacity and Increased Reactive Oxygen Species Production During Aging in the Brown Norway Rat
Oxidative stress epididymis glutathione peroxidase superoxide dismutase reproduction sperm
2008/12/24
As the proportion of aged males attempting to reproduce continues to rise, so does the concern regarding the quality of spermatozoa from aged men. An imbalance between the generation of reacti...
Testosterone Replacement Therapy for Male Aging：ASA Position Statement
Testosterone Replacement Therapy Male Aging ASA Position Statement
2008/12/23
The American Society of Andrology suggests that testosterone replacement therapy in aging men is indicated when both clinical symptoms and signs suggestive of androgen deficiency and decreased testo...
Rho-kinase Inhibition Improves Erectile Function in Aging Male Brown-Norway Rats
Muscle smooth drug effects penis physiology biological aging penile erection
2008/12/23
Physiological aging is a significant risk factor in the on-set of male erectile dysfunction (ED) and an imbalance in factors that modulate cavernosal smooth-muscle tone may play a role in these altere...