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Osteoprotegerin and Ligand of Receptor Activator of Nuclear Factor
Tooth movement RANKL OPG Ovariectomy Periodontal ligament
2010/3/5
Objective: To test the null hypothesis that increased tooth displacement in ovariectomized rats is not related to differential expressions of OPG and RANKL in the periodontium.
Materials and Method...
Failure to prevent decompression illness in rats by pretreatment with a soluble complement receptor
decompression complemen timmune rat animal
2009/3/28
Controversy exists over the role of complement activation in the natural history of decompression illness (DCI), and whether an individual's predisposition to DCI might be influenced by susceptibility...
Organotin-Induced Toxicity and Nuclear Receptor Signaling
organotin aromatase endocrine disruptor retinoid X receptor (RXR) peroxisome proliferator-activated receptor (PPAR) γ
2009/3/23
Organotin compounds have been widely used as agricultural fungicides, rodent repellents, and molluscicides and in antifouling paints for ships and fishing nets. These widespread uses have resulted in ...
Cytosolic Ca2+ alteration mediates both ryanodine receptor and IP3 receptor in TE671/RD cells
Cytosolic Ca2+ alteration mediates ryanodine receptor IP3 receptor TE671/RD cells
2009/3/3
TE671/RD is a cell line obtained from the rhabdomyosarcoma cells. In the present study, we examined [Ca2+]i alteration induced by acetylcholine (ACh) in TE671/RD cells with the special attention to ...
Characterization of prostaglandin E receptor subtypes involved in the relaxation of rabbit penile corpus cavernosum smooth muscle
prostaglandin E receptor subtypes rabbit penile corpus cavernosum smooth muscle
2009/3/3
Prostaglandin E (PGE) induces the penile erection in the mammalians. Receptors for PGE were characterized to 4 different subtypes (EP1—4). The effects of agonists for EP1—4 receptors were studied on...
Daily increase of fat ingestion mediated via mu-opioid receptor signaling pathway
fat ingestion mu-opioid receptor signaling pathway
2009/3/2
We investigated the involvement of opioid receptors such as the mu and delta receptors in the predominant elevation of corn oil appetite just after 5-day repeated treatment of corn oil ingestion. Ra...
Possible activation of murine T lymphocyte through CD98 is independent of interleukin 2/interleukin 2 receptor system
murine T lymphocyte CD98 interleukin 2/interleukin 2 receptor system
2009/3/2
CD98 is a widely expressed cell surface heterodimetric protein of 125 kDa. Its expression is upregulated during lymphocyte activation induced by mitogen, superantigen, conventional antigen, and a co...
Effects of long-term estradiol treatment on the contractile response to muscarine and muscarinic receptor subtypes in the bladder of aged female rats
long-term estradiol treatment contractile muscarine muscarinic receptor subtypes
2009/3/2
In this study, we tried to elucidate the effect of estrogen treatment on the detrusor contractile response to muscarine and muscarine receptor subtypes of the bladder in 13-month-old female Wistar r...
N-hexacosanol prevents diabetes-induced rat ileal dysfunction without qualitative alteration of the muscarinic receptor system
N-hexacosanol diabetes-induced rat qualitative alteration muscarinic receptor system
2009/3/2
We evaluated the effects of N-hexacosanol, a cyclohexenonic long-chain fatty alcohol, on muscarinic receptors in diabetic rat ileal dysfunction. Eight-week-old male SD rats were divided into four gr...
The involvement of urothelial α1A adrenergic receptor in controlling the micturition reflex
urothelial α1A adrenergic receptor micturition reflex
2009/3/2
The current study was undertaken in an attempt to characterize the functional properties of urothelial α1A adrenergic receptors, especially in modulating the micturition reflex. The expression of α1...
Urothelium EP1 receptor facilitates the micturition reflex in mice
Urothelium EP1 micturition reflex mice
2009/3/2
We investigated the presence of EP1 receptor in the urothelium and its role in micturition reflex by examining the effect of intravesical administration of prostaglandin E2 (PGE2), an EP1 agonist (O...
Rat wild-type parathyroid hormone receptor（PTH-R）and mutant PTH-RP132L show the different intracellular localization in vitro
Rat wild-type parathyroid hormone receptor（PTH-R） mutant PTH-RP132L
2009/3/2
A replacement of proline with leucine at position 132 of the receptor for parathyroid hormone (PTH)/parathyroid hormone-related peptide (PTHrP), i.e., PTH-R, has been discovered in human Blomstrand'...
Pirh2 interacts with and ubiquitylates signal recognition particle receptor β subunit
Pirh2 interacts ubiquitylates signal recognition particle receptor β subunit
2009/3/2
Pirh2 is a RING finger type ubiquitin ligase which ubiquitylates various proteins including p53, p27Kip1, HDAC1, and ε-COP. In this study, we identified signal recognition particle receptor β subuni...
Significant association of interleukin 10 receptor mRNA levels with renal cell carcinoma metastasis
mRNA renal cell carcinoma metastasis
2009/3/2
Immunosuppressive cytokine, interleukin 10 (IL-10), is associated with progression of the renal cell carcinoma (RCC). However, the roles of its cell surface receptor, interleukin 10 receptor (IL-10R...
Sex steroid inhibition of LH induction of the LH receptor
estrogen testosterone luteinizing hormone receptor testis Leydig cell
2009/2/23
Testosterone and estrogen were tested as possible mediators of the prolactin-dependent LH induction of LH receptors in hypophysectomized adult male rats. Animals were injected s.c. with saline, pr...