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Increased incidence of allergic disorders and elevated food-specific serum IgG4 levels in Japanese patients with Crohn's disease
allergic disorder food allergy IgE IgG4 inflammatory bowel disease
2010/11/29
An allergic response to foreign intestinal antigens such as those contained in food has been implicated as a causative factor in the development of inflammatory bowel disease (IBD). In this study, we ...
Reliability and Validity of the Self-report Quality of Life Questionnaire for Japanese School-aged Children with Asthma (JSCA-QOL v.3)
asthma quality of life questionnaire reliability and validity school-aged children
2010/11/18
The present study showed that the JSCA-QOL v.3 is a reliable and valid measurement tool that can be used to appropriately assess QOL in school-aged children with asthma. As the JSCA-QOL v.3 can be eas...
Treatment and management of severe asthma in childhood through to young adult patients: 12th Japanese Society of Allergology Meeting, Spring Clinical Meeting, Lecture of the Chairman
adolescence asthma death bronchial asthma epidemiology infantile asthma young adult
2010/11/25
Asthma treatments have changed radically due to elucidation of morbidity and development of medicine/treatment strategies. The Global Initiative for Asthma consists of a six-part asthma management pro...
Effect of modified immunotherapy with an allergen-pullulan conjugate in patients with Japanese cedar pollinosis
eosinophil immunotherapy Japanese cedar pollinossis mast cell seasonal allergic rhinitis Th1 cytokine Th2 cytokine
2010/11/25
Immunologic mechanisms of allergen immunotherapy are still incompletely understood. Immunotherapy of a higher maximum tolerance dose with reduced risks of systemic reactions, such as anaphylaxis, need...
Peak expiratory flow in normal healthy Japanese adults: Comparisons with values reported in other races
comparisons with other races normal Japanese adults peak expiratory flow regression equations ventilatory capacity
2010/11/24
From the regression equations, predicted values of PEF can be derived for any Japanese adult aged 15-74 years. We were able to obtain predicted equations for PEF in normal Japanese adults using both ...
Japanese cedar pollen in floating indoor house dust after a pollinating season
highly sensitive Cry j1 assay house dust Japanese cedar pollen Japanese cedar pollinosis self-care
2010/11/22
The results showed that, indoors, a lot of Japanese cedar pollen (JCP) was found on the floor (tatami mats, carpets), sofas and curtains. The number of JCP in living rooms peaked in April after the po...
Effect of fexofenadine on the quality of life of Japanese cedar pollinosis patients
allergic rhinitis cedar pollinosis daily life fexofenadine quality of life
2010/11/22
Background: The aim of the present survey was to investigate the changes associated with fexofenadine administration in the quality of life (QOL) of Japanese cedar pollinosis patients.
Methods: After...
Polymorphism of LPL Locus in Japanese and Comparison of PCR Amplification Efficiency from Degraded DNA between LPL Locus and the D21S11
Short tandem repeat LPL Japanese population
2010/12/1
The short tandem repeat (STR) polymorphism of the lipoprotein lipase (LPL) locus was amplified by PCR and analyzed using denaturing polyacrylamide gel electrophoresis followed by silver staining. Amon...
Lack of Association between Atopic Dermatitis and -401A/G Polymorphism in the Promoter Region of the RANTES Gene in Japanese
atopic dermatitis IgE polymorphism RANTES
2010/11/22
Background: Regulated on activation, normal T expressed and secreted (RANTES) has been known to be deeply involved in the pathophysiology of atopic dermatitis (AD). To examine whether a -401A/G polymo...
Development of the Revised Final Version of the Quality of Life of Japanese School Aged Children with Asthma Questionnaire: The Characteristics of the Low QOL Scoring Group and Development of an Evaluation Form
adolescent asthma children evaluation form quality of life
2010/11/22
A total of 2097 children with asthma, who fully completed the questionnaire, were included in the study. As a result of analysis, it was clear that the characteristics of the low score group (under th...
Survey of Food and Airborne Allergen-specific IgE Levels in a General Population of 3-year-old Japanese Children
3-year-old children antigen-specific IgE pollen serum total IgE
2010/11/22
The mean total IgE level of all subjects was 34.7 IU/ml, while that for the Kanto and Asahikawa areas was 44.7 and 22.5 IU/ml, respectively. Twenty six percent of the 612 children were judged positive...
Recent Developments in Genetic Study of Allergic Disease in the Japanese Population
allergic disease asthma atopy Japanese linkage polymorphism
2010/11/19
Allergy is a common immune disorder characterized by raised IgE levels, which leads to clinical disorders such as asthma, rhinitis and eczema. Our understanding of the pathogenesis of allergic disease...
Validation Study of a Disease-specific Module, the Asthma Health Questionnaire (AHQ) Using Japanese Adult Asthmatic Patients
adult asthma Face Scale Japanese quality of life questionnaire
2010/11/22
Each item of the AHQ-37 was well accepted by the patients with answering rates of 95 to 100%. Six subscales (Asthmatic Symptoms, Emotion, Daily Activity, Factors which Worsened Symptoms, Social Activi...
The Clinical Evaluation of the Acceptance of Fluticasone Propionate Diskus® by Older Japanese Patients with Bronchial Asthma
asthma drug compliance Fluticasone propionate Diskus® older patients
2010/11/22
The mean required times (seconds) were significantly different between patients aged 75 years or older, and with patients less than 65 years of age; 45.8 ± 8.1 vs. 31.8 ± 12.3 (p = 0.046) in the BDP g...
The 2002 Japanese Pediatric Guideline for the Treatment and Management of Asthma
asthma children guideline Japan
2010/11/19
The Japanese Pediatric Asthma Guideline was revised in November of 2002. The guideline, the JPGL2002, has several characteristics different from other asthma guidelines. One of the important differenc...