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中国科学院动物研究所专利：Fusion protein for inducing pluripotent stem cells and application method thereof
中国科学院动物研究所 专利 哺乳动物 YAP蛋白 转录控制活性
2024/5/31
提供了由哺乳动物YAP蛋白或具有转录控制活性的片段的融合蛋白的与细胞全能性和转录激活结构域相关的基因编码的蛋白、编码核苷酸序列、表达载体及其组合物，以及使用该融合蛋白诱导多能干细胞的方法。
中国科学院动物研究所专利：Delayed senescence, malignant conversion of human mesenchymal stem cells can be a resistor, its preparation and use
中国科学院动物研究所 专利 人骨髓间 充质干细胞
2024/5/30
延缓衰老，制备恶性人骨髓间充质干细胞的方法可抗选择性。 制备方法， 第二密码子的253个氨基酸残基的FOXO3蛋白， 丝氨酸密码子编码丙氨酸突变的密码子，FOXO3蛋白密码子的第315位氨基酸残基，丝氨酸密码子编码丙氨酸突变的密码子编码2个突变中的一个突变，编码多能干细胞的基因组包括该步骤。 制备的重组间充质干细胞，并进一步提供其在移植治疗中的用途。 [附图]
脊髓损伤(Spinal Cord Injury, SCI)引起的原发性和继发性白质损伤会导致长期的运动功能缺陷，通过在受损的轴突和目标神经元之间插入新的神经元可以实现功能连接的重建，神经干细胞(Neural Stem Cells, NSCs)有望在脊髓损伤断端之间重建通信。然而，SCI后形成的抑制性微环境往往导致内源性和移植的NSCs向胶质细胞而不是神经元分化。已有研究表明，功能生物材料可减轻SC...
NSF-funded researchers have created better biosensor technology using a newly developed instrument that may lead to safe stem cell therapies for treating Alzheimer's and Parkinson's diseases and other...
加州大学圣地亚哥分校医学院的研究人员在当前在线期刊《Stem Cells and Development》杂志上撰文，描述了一种快速，经济有效的从原代细胞中制造人皮层类器官的方法。
2017冷泉港亚洲会议：干细胞，老化和复兴（Cold Spring Harbor Asia conference on Stem Cells,Aging&Rejuvenation ）
2017 冷泉港亚洲 会议 干细胞 老化 复兴
2017/2/13
We are pleased to announce the 1st Cold Spring Harbor Asia conference on Ubiquitin Family, Autophagy and Diseases which will be held in Suzhou, China, located approximately 60 miles west of Shanghai. ...
Stem Cells Step Forward
Stem Cells Step Forward
2017/3/13
Researchers at Harvard Medical School and Boston Children’s Hospital were able, for the first time, to use patients’ own cells to create cells similar to those in bone marrow and then use them to iden...
Gordon Research Conference on Tissue Niches & Resident Stem Cells in Adult Epithelia
Tissue Niches Resident Stem Cells
2016/7/29
Adult epithelia regenerate during adult life due to the constant activity of stem cell pools. Stem cells maintain tissue homeostasis and repair injury by close communication with their tissue environm...
Scientists pinpoint genes that make stem cells in plants,revealing origin of beefsteak tomatoes（图）
Scientists stem cells in plants origin of beefsteak tomatoes
2015/6/2
A team of scientists at Cold Spring Harbor Laboratory (CSHL) has identified a set of genes that control stem cell production in tomato. Mutations in these genes explain the origin of mammoth beefsteak...
Derivation of endothelial colony forming cells from human cord blood and embryonic stem cells
Embryonic Stem Cells Directed Differentiation Human Umbilical Cord Blood
2015/5/25
Endothelial Colony Forming Cells (ECFCs) are highly proliferative endothelial progenitor cells with clonal proliferative potential and in vivo vessel forming ability. While endothelial cells have been...
Characterization of Bovine NANOG5′-flanking Region during Differentiation of Mouse Embryonic Stem Cells
Bovine Embryonic Stem Cell NANOG Promoter Neural Differentiation Adipocyte Differentiation
2016/5/19
Embryonic stem cells (ESCs) have been used as a powerful tool for research including gene manipulated animal models and the study of developmental gene regulation. Among the critical regulatory factor...
HOUSTON — (Oct. 31, 2014) — In the first study of its kind, Rice University researchers have mapped how information flows through the genetic circuits that cause cancer cells to become metastatic. The...
HOUSTON — (Oct. 31, 2014) — In the first study of its kind, Rice University researchers have mapped how information flows through the genetic circuits that cause cancer cells to become metastatic. The...
Critical transport: Bond LSC team finds boron vital for plant stem cells, corn reproduction（图）
transport Plant stem cells corn reproduction
2014/9/1
Carbon’s next-door neighbor on the periodic table typically receives little attention, but when it comes to corn reproduction boron fills an important role.
Analysis of differentiation capacity of Cfp1 null embyronic stem cells
Stem Cells Cell Differentiation Epigenetics DNA Methylation Mice Cardiomyocytes Neurons Leukemia Inhibitory Factor
2015/5/22
Epigenetics is defined as “the study of stable, often heritable, changes that influence gene expression that are not mediated by DNA sequence” (Fingerman et al., 2013). Epigenetic marks such as covale...