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African American adolescents have inadequate self-management behaviors, particularly during middle adolescence (14-16 years of age). Inaccurate beliefs, degree of asthma impairment (well controlled or...
Immune and inflammatory responses mediated by cytokines, play important roles in the pathophysiology of asthma. These responses are associated with overexpression of Th2 cytokines such as IL-4 and I...
Immune and inflammatory responses mediated by cytokines, play important roles in the pathophysiology of asthma. These responses are associated with overexpression of Th2 cytokines such as IL-4 and I...
Although sulfidopeptide leukotrienes (sLT) are considered to play an important role in the pathogenesis of asthma, their precise action has not been elucidated in asthmatics during exacerbation. In th...
Early introduction of inhaled steroids as a treatment for childhood asthma is recommended in the guidelines to achieve not only early control of symptoms with an improvement in patients' quality of li...
Background: Signal transducers and activators of transcription 6 (Stat6) is a key transcription factor involved in interleukin (IL)-4 and IL-13-mediated biological responses. Recently, we reported the...
Twenty-two patients were assessed as responders according to our criteria. The percentage of blood eosinophil (%EOS, P = 0.015) and basophil (%BASO, P = 0.019) counts were identified as significant va...
In the past decade it has become clear that asthmatic patients who are clinically unresponsive, or ”resistant” to glucocorticoid therapy may have T cells which manifest resistance to glucocorticoid in...
Asthma is a complex disorder of inflammation and remodelling largely restricted to the conducting airways. It is a disorder where there are major genetics and environmental factors that interact toget...

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