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Researchers from Harvard’s Stem Cell and Regenerative Biology (HSCRB)’s Zon lab have discovered a new mechanism that influences melanoma development, a finding that could have wide implications for pa...
Malignant melanoma is one of the rare and highly aggressive diseases of the sinonasal cavity. High index of suspicion is required for diagnosis as the patient usually presents with non specific signs ...
Much of the resistance of melanoma to immunotherapy, radiotherapy and cytotoxic treatment is due to an impressive array of molecular defences that derive ultimately from the essential molecular struct...
In the early 20th Century, excision of all primary melanomas with >5cm clearance margins was recommended, with amputation in selected cases – recommendations based on experience of a few patients with...
This edition of Cancer Forum reports a series of papers prepared for a Festschrift held in honour of Emeritus Professor William McCarthy AM at the Royal Prince Alfred Hospital on 29 July 2005. Profes...
Over the past 25 years, surgical strategies for the management of primary cutaneous melanoma have changed considerably. In the 1970s and 1980s, most melanomas were widely excised with 3cm-5cm margins...
Melanoma is an aggressive skin cancer with an increasing incidence worldwide. It is particularly common in Australia and New Zealand, where it is a major health issue that is responsible for the deat...
Despite major advances in the treatment of many solid tumours, metastatic melanoma remains stubbornly resistant to therapeutic attack with systemic agents. Much of the resistance of melanoma to immun...

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