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Two modeling strategies for empirical Bayes estimation
f-modeling g-modeling Bayes rule in terms of f
2015/8/20
Empirical Bayes methods use the data from parallel experiments, for instance observtions Xk N (k;1) for k = 1;2; : : : ; N, to estimate the conditional distributions kjXk.
There are two main estima...
Polygenic Modeling with Bayesian Sparse Linear Mixed Models
Polygenic Modeling Bayesian Sparse Linear Mixed Models
2012/11/23
Both linear mixed models (LMMs) and sparse regression models are widely used in genetics applications, including, recently, polygenic modeling in genome-wide association studies. These two approaches ...