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ONTOLOGY-DRIVEN AND NETWORK–ENABLED SYSTEMS BIOLOGY CASE STUDIES
bioinformatics Integration of genomics
2015/5/27
With the progress in high-throughput technologies and bioinformatics in recent years, it is possible to determine to what extent genetic or environmental manipulation of a biological system affects th...
Biophysical studies of cholesterol in unsaturated phospholipid model membranes
EPA DHA Solid State Deuterium NMR Membrane Domains Cholestane
2015/1/19
Cellularmembranescontainastaggeringdiversityoflipids.Thelipidsareheterogeneously
distr
ibutedtocreateregions,ordomains,whosephysicalpropertiesdifferfromthebulk
membraneandplayanessentialroleinmodul...
Biophysical Studies of Axonal Transport
Intracellular Transport Kinesin-1 Microtubule Motor Protein
2014/12/10
Intracellular transport provides a mechanism by which cellular material, such as organelles, vesicles, and protein, can be actively transported throughout the cell. This process relies on the activity...
Computational Potential Energy Minimization Studies on the Prion AGAAAAGA Amyloid Fibril Molecular Structures
Computational Potential Energy Minimization Amyloid Fibril Molecular Structures Biological Physics
2012/5/3
X-ray crystallography, NMR (Nuclear Magnetic Resonance) spectroscopy, and dual polarization interferometry, etc are indeed very powerful tools to determine the 3D structures of proteins (including the...
Computational Studies of the Structural Stability of Rabbit Prion Protein Compared to Human and Mouse Prion Proteins
Neurodegenerative Diseases Prion Diseases Immunity Rabbit Prion Protein Rabbit NMR X-ray and Homology Structures
2011/8/11
Abstract: Prion diseases are invariably fatal and highly infectious neurodegenerative diseases affecting humans and animals. The neurodegenerative diseases such as Creutzfeldt-Jakob disease, variant C...