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Erratum for Traber et al. α-Tocopherol disappearance rates from plasma depend on lipid concentrations: studies using deuterium-labeled collard greens in younger and older adults. Am J Clin Nutr 2015;101:752–9
Traber plasma deuterium-labeled collard greens
2018/11/13
Erratum for Traber et al. α-Tocopherol disappearance rates from plasma depend on lipid concentrations: studies using deuterium-labeled collard greens in younger and older adults. Am J Clin Nutr 2015;1...
Get a clue:Biochemist studies fruit fly to understand Parkinson's disease,muscle wasting
Biochemist fruit fly Parkinson's disease muscle wasting
2016/7/4
The fruit fly may help us be less clueless about human muscle development and Parkinson's disease.Erika Geisbrecht, Kansas State University associate professor of biochemistry and molecular biophysics...
Ultrafast Excited-State Dynamics in the Green Fluorescent Protein Variant S65T/H148D.1.Mutagenesis and Structural Studies
Arabidopsis thaliana homogentisate phytyltransferase (HPT/VTE2) Lactuca sativa tocopherol tocopherol cyclase (TC/VTE1) vitamin e.
2016/5/24
Wild type green fluorescent protein (wt-GFP) and the variant S65T/H148D each exhibit two absorption bands, A and B, which are associated with the protonated and deprotonated chromophores, respectively...
Synthesis of a Thymidine Phosphoramidite Labelled with 13C at C6: Relaxation Studies of the Loop Region in a 13C Labelled DNA Hairpin
Thymidine Phosphoramidite Labelled 13C C6 Relaxation Studies 13C Labelled DNA Hairpin
2016/5/20
A thymidine phosphoramidite labelled at C6 with 13C has been synthesized, and incorporated into a synthetic oligonucleotide, d(CGCGT*T*GT*T*CGCG), which adopts a hairpin conformation. NMR relaxation m...
Chemically Induced Dynamic Nuclear Polarization Studies of Yeast tRNAPhe
Chemically Induced Dynamic Nuclear Polarization Studies Yeast tRNAPhe
2016/5/20
Chemically induced dynamic nuclear polarization (CIDNP) has been observed from yeast tRNAPhe following reaction with photoexcited riboflavin. At 20 OC, several resonances of tRNA in the native form sh...
Chemically Induced Dynamic Nuclear Polarization Studies of Guanosine in Nucleotides,Dinucleotides,and Oligonucleotides
Chemically Induced Dynamic Nuclear Polarization Studies Guanosine Nucleotides Dinucleotides Oligonucleotides
2016/5/20
The nuclear magnetic resonance (NMR) technique of chemically induced dynamic nuclear polarization (CIDNP) has been used to study the reactions between photoexcited flavins and a wide variety of nucleo...
This thesis describes separations performed by Pressurized Planar Electrochromatography (PPEC), which is a chromatographic method developed at IUPUI. In PPEC the mobile phase is driven by electroosmot...
Toward an antibody peptidase: Mechanistic studies of peptide-bond hydrolysis
Antibody peptide enzyme hydrolysis peptide peptide bond hydrolysis temperature primary amine derivatives
2014/12/11
To maximize the probability of obtaining an antibody peptidase, an efficient assay for the hydrolysis of peptide bonds was developed. Two methods for detecting the uncatalyzed rate of hydrolysis of a ...
Studies of the complex of ribosomal protein L1 with its binding site in 23S rRNA: Modification -interference, mutagenesis and crosslinking
Ribosomal proteins escherichia coli ribosomes the protein spiral protein
2014/12/11
Interaction of ribosomal protein L1 and the 23S rRNA plays an important role in both the structure and biological activity of the Escherichia coli ribosome. We have minimized the binding site for prot...
New Insights in the TSSK Family: Studies in the Activity and Function of the Testis Specific Serine Kinases
Capza3 Gamete Fusion Izumo Kinase Mouse sperm Tssk
2014/12/10
The Testis Specific Serine Kinase (Tssk) family of proteins is a large group of kinases that present high level of conservation within paralogs, as well as within species. In addition, in all reported...
Structural studies of membrane-assembled PopD and PopB, the Pseudomonas aeruginosa type 3 secretion translocators
Pure sciences Biological sciences Fluorescence Membrane proteins Membranes Pore formation Type III secretion
2014/12/10
Transport of proteins across membranes is essential during many stages of pathogen infection and colonization of human cells. Many Gram-negative pathogens use a Type 3 Secretion (T3S) system to inject...
Structural And Biochemical Studies Of The Human Lysosomal Enzymes: N-Acetylgalactosamine-6-Sulfatase, N-Sulfoglucosamine Sulfohydrolase And Beta-Galactosidase
Pure sciences Biological sciences Cysteine modification Enzyme replacement therapy Lysosomal storage disease Pharmacological chaperone therapy Sulfatase structure X-ray crystallography
2014/12/10
Lysosomal storage diseases are disorders caused by deficiencies of enzymes responsible for the degradation of substances present in lysosomes. The loss of activity of a lysosomal enzyme leads to the a...
Methodological Issues in Multistage Genome-Wide Association Studies
Methodological Issues Multistage Genome-Wide Association Studies
2010/11/16
Because of the high cost of commercial genotyping chip technologies, many investigations have used a two-stage design for genome-wide association studies, using part of the sample for an initial disco...
Yale Immunobiologist Wins Prestigious Rosenstiel Award For Pioneering Studies of Innate Immune System(图)
Yale Immunobiologist Prestigious Rosenstiel Award Innate Immune System
2009/12/15
Yale School of Medicine immunobiologist Ruslan Medzhitov, Ph.D., David W. Wallace Professor of Immunobiology and Howard Hughes Medical Institute Investigator, has been awarded the 2010 Lewis S. Rosens...