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Twist1 and Etv5 are part of a transcription factor network defining T helper cell identity
Twist1 Etv5
2015/5/21
CD4 T helper cells control immunity to pathogens and the development of inflammatory disease by acquiring the ability to secrete effector cytokines. Cytokine responsiveness is a critical component of ...
The Fanconi anemia signaling network regulates the mitotic spindle assembly checkpoint
cancer mitosis cell division
2015/5/21
anconi anemia (FA) is a heterogenous genetic syndrome characterized by progressive bone marrow failure, aneuploidy, and cancer predisposition. It is incompletely understood why FA-deficient cells deve...
NETWORK BIOLOGY: UNDERSTANDING THE CELL’S FUNCTIONAL ORGANIZATION
NETWORK BIOLOGY THE CELL’S FUNCTIONAL ORGANIZATION
2014/3/31
A key aim of postgenomic biomedical research is to systematically catalogue all molecules and
their interactions within a living cell. There is a clear need to understand how these molecules and
the...