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Cholecystokinin responsiveness varies across the population dependent on metabolic phenotype
cholecystokinin obesity drug development hormonal responsiveness population study cholesterol epidemiology
2018/11/15
Background: Cholecystokinin (CCK) is an important satiety factor, acting at type 1 receptors (CCK1Rs) on vagal afferent neurons; however, CCK agonists have failed clinical trials for obesity. We postu...