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Fibrosis is the thickening of various tissues caused by the deposition of fibrillar extracellular matrix (ECM) in tissues and organs as part of the body’s wound healing response to various forms of da...
Alterations of Vertical Jump Mechanics after a Half-Marathon Mountain Running Race
Countermovement jump post-activation potentiation force-velocity relationship ensemble-average mechanics
2016/7/7
The fatiguing effect of long-distance running has been examined in the context of a variety of parameters. However, there is scarcity of data regarding its effect on the vertical jump mechanics. The p...
Cutting Mechanics: Relation to Performance and Anterior Cruciate Ligament Injury Risk
TURNING KINEMATICS KNEE AGILITY PREVENTION
2017/4/19
Purpose: Quick changes of direction during running (cutting) are necessary for successful performance of many sports but are associated with noncontact anterior cruciate ligament (ACL) injuries. Curre...
Multi-scale analysis of morphology, mechanics, and composition of collagen in murine osteogenesis imperfecta
Atomic force microscopy Raman spectroscopy Reference point indentation MicroCT crystallinity modulus
2015/1/12
Osteogenesis imperfecta is a rare congenital disease commonly characterized by brittle bones caused by mutations in the genes encoding Type I collagen, the single most abundant protein produced by the...
Penn Researchers Model the Mechanics of Cells’ Long-range Communication
Penn Researchers Model Mechanics of Cells Long-range Communication
2014/12/30
Interdisciplinary research at the University of Pennsylvania is showing how cells interact over long distances within fibrous tissue, like that associated with many diseases of the liver, lungs and ot...
Multiscale analysis of morphology and mechanics in tail tendon from the ZDSD rat model of type 2 diabetes
AFM tension nanoscale
2014/12/4
Type 2 diabetes (T2D) impacts multiple organ systems including the circulatory, renal, nervous and musculoskeletal systems. In collagen-based tissues, one mechanism that may be responsible for detrime...
Effects of tissue hydration on nanoscale structural morphology and mechanics of individual Type I collagen fibrils in the Brtl mouse model of Osteogenesis Imperfecta
AFM Ultrastructure Genotype/phenotype D-periodic spacing Modulus Energy
2014/11/6
Type I collagen is the most abundant protein in mammals, and is a vital part of the extracellular matrix for numerous tissues. Despite collagen’s importance, little is known about its nanoscale morpho...
Multi-scale Analysis of Bone Chemistry, Morphology and Mechanics in the oim Model of Osteogenesis Imperfecta
Atomic force microscopy Raman Spectroscopy Reference Point Indentation MicroCT Crystallinity Modulus
2014/11/6
Osteogenesis imperfecta is a congenital disease commonly characterized by brittle bones and caused by mutations in the genes encoding Type I collagen, the single most abundant protein produced by the ...
Multiscale analysis of morphology and mechanics in tail tendon from the ZDSD rat model of type 2 diabetes
AFM Tension Nanoscale Ultrastructure Modulus
2014/11/6
Type 2 diabetes (T2D) impacts multiple organ systems including the circulatory, renal, nervous and musculoskeletal systems. In collagen-based tissues, one mechanism that may be responsible for detrime...
Fracture mechanics of the human femoral neck: effect of density of the cancellous core
Fracture mechanics the human femoral neck the cancellous core
2010/1/7
Fracture mechanics of the human femoral neck: effect of density of the cancellous core.
Mechanobiology and the microcirculation:cellular,nuclear and fluid mechanics
Nuclear mechanics Hutchinson Gilford progeria syndrome computational fluid dynamics (CFD)
2009/12/23
Endothelial cells are stimulated by shear stress throughout the vasculature and respond
with changes in gene expression and by morphological reorganization. Mechanical
sensors of the cell are varied...
Optimal Loading Conditions for Controlled Movement of Anterior Teeth in Sliding Mechanics
Sliding mechanics Power arm Anterior teeth retraction Finite element method Deformation of archwire
2010/3/9
Objective: To determine optimal loading conditions such as height of retraction force on the power arm and its position on the archwire in sliding mechanics.
Materials and Methods: A 3D finite elemen...
The effects of increased gas density on pulmonary mechanics
nitrogen human neon pulmonary respiratory Helium Work of Breathing
2009/7/20
The effects of increased gas density on pulmonary mechanics.
Influence of hydrostatic compression of the chest and intrathoracic blood pooling on static lung mechanics during head-out immersion
human immersion intrathoracic blood pooling respiratory
2009/7/20
The effect of water immersion on static lung volumes and pressure-volume curves was studied in five subjects. A special container allowed measurements during nonimmersion, head-out immersion, and thor...
Pulmonary mechanics and atelectasis during immersion in oxygen-breathing subjects
human Pulmonary mechanics atelectasis oxygen immersion
2009/7/14
It has been suggested that vital capacity (VC) reduction seen during head-out immersion and oxygen breathing is due to atelectasis formation. In this study VC was reduced in 8 healthy subjects by 8.7p...