搜索结果: 1-5 共查到“医学 binding proteins”相关记录5条 . 查询时间(0.072 秒)
Although only 10 percent of amyotrophic lateral sclerosis (ALS) cases are hereditary, a significant number of them are caused by mutations that affect proteins that bind RNA, a type of genetic materia...
Dissecting the expression landscape of RNA-binding proteins in human cancers
RNA-binding proteins cancer pathogenesis
2015/3/5
Background RNA-binding proteins (RBPs) play important roles in cellular homeostasis by controlling gene expression at the post-transcriptional level. Results We explore the expression of more than 800...
Copper Binding of Nuclear RNA- and DNA-Binding Proteins p54nrb/NonO and PSF
copper p54nrb/Non-POU-domain-containing octamer binding protein (p54nrb/NonO) polypyrimidine tract-binding protein-associated splicing factor (PSF) nucleus
2009/3/23
The biological function of nuclear copper in mammalian cells is poorly understood because little is known about specific binding protein(s) for nuclear copper. We recently purified that p54nrb/Non-POU...
Actin and actin-binding proteins in bovine spermatozoa：potential role in membrane remodeling and intracellular signaling during epididymal maturation and the acrosome reaction
proteins bovine spermatozoa potential role signaling epididymal maturation
2008/12/26
The actin cytoskeleton influences a wide range of functions in nonmuscle somatic cells, including shape, movement, and interactions with extracellular matrices. The role of actin in mammalian male ger...
Smad及其结合蛋白在TGF β信号传导中的功能Functions of Smad and Its Binding Proteins in TGF β Signal Pathway
Smad TGF β 靶基因 信号传导
2007/12/31
摘要转化生长因子β超家族的细胞因子在细胞生长发育和分化、物质代谢等方面都有极其重要的作用，这种多功效性决定在细胞内必然存在复杂的TGF β信号传导通路。Smad是TGF β超家族信号传导的下游因子，介导TGF β信号从胞质中传入细胞核，特异性调节TGF β靶基因的表达。最近的研究发现与Smad结合的蛋白因子，包括转录因子、活化因子和抑制因子等在Smad特异性识别和调控TGF β靶基因表达的过程中起...