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Identification, kinetic and structural characterization of small molecule inhibitors of aldehyde dehydrogenase 3a1 (Aldh3a1) as an adjuvant therapy for reversing cancer chemo-resistance
cyclophosphamide chemosensitivity structure activity relationships cell culture
2015/5/25
ALDH isoenzymes are known to impact the sensitivity of certain neoplastic cells toward cyclophosphamides and its analogs. Despite its bone marrow toxicity, cyclophos-phamide is still used to treat var...
Alterations of Kinetic Characteristics in Step Up and Over Test in Patients with Anterior Cruciate Ligament Deficiency
Knee ACL deficiency kinetics locomotion step activity
2015/5/5
The purpose of this study is to investigate the alterations of kinetic characteristics in the step up/over test in patients with acute and chronic anterior cruciate ligament (ACL) deficiency. Twenty a...
Combined Hamartoma of the Optic Disc and Retinal Pigment Epithelium—3 Years of the Follow-Up with Semi-Automated Kinetic Perimetry
Hamartoma Perimetry Optic Disc
2013/1/31
Aim: To present a case of hamartoma of the optic disc and Retinal Pigment Epithelium (RPE) and follow up of the visual function over three-years period. Methods: A seventeen-year-old boy has observed ...
Kinetic polymerization behavior of fluorinated monomers for dental use
Polymerization kinetics Fluorinated monomer
2010/11/30
The kinetic polymerization behavior of 2,2,2-trifluoroethyl methacrylate (TFEMA), 1,1,1,3,3,3-hexafluoroisopropyl methacrylate (HFIPMA), 2,2,2-trifluoroethyl acrylate (TFEA) and 1,1,1,3,3,3-hexafluoro...
Kinetic mechanism reduction based on an integer programming approach
Kinetic mechanism reduction an integer programming approach
2009/12/24
Kinetic mechanism reduction based on an integer programming approach.
Design of flexible reduced kinetic models
flexible reduced kinetic models detailed chemistry
2009/12/24
Design of flexible reduced kinetic models.
New approaches for representing, analyzing and visualizing complex kinetic mechanisms
complex kinetic mechanisms combustion visualization
2009/12/24
Complex kinetic representations involving thousands of reacting species and tens of
thousands of reactions are currently required for the rational analysis of modern
combustion systems. In order t...
Kinetic Spectrofluorometric Determination of Certain Calcium Channel Blockers via Oxidation with Cerium (IV) in Pharmaceutical Preparations
verapamil hydrochloride diltiazem hydrochloride nicardipine hydrochloride Cerium (IV)
2009/10/30
A simple and sensitive kinetic spectrofluorometric method was developed for the determination of some calcium channel blockers namely, verapamil hydrochloride, diltiazem hydrochloride, nicardipine hyd...
Purification of Casein Kinase II From Lung Tissue and Kinetic Evaluations With Polyamines and Myc-Oncoprotein
Casein kinase II olyamines yc ell proliferation abbreviations KII-casein kinase II myc-phosphorylated myc oncoprotein Pmax-phosphorylated max protein
2009/7/2
The overall goal of this study was to seek molecular linkages between polyamines, casein kinase II, and the myc oncoprotein by using a cell-free, highly purified enzyme kinetic analysis. Casein kinase...
Problems in Urinary Iodine Determination Methods and an Automated Kinetic Assay As a Solution
Iodine ammonium persulfate digestion photometric assay urine automation
2009/6/25
Accurate, fast and economical urinary iodine measurement is very important in diagnosing iodine deficiency disorders. The urinary iodine determination method using ammonium persulfate digestion based ...
Kinetic Determination of Ribavirin in Drug Formulation
spectrophotometry ribavirin potassium permanganate dosage forms
2009/4/20
Two simple and sensitive kinetic methods were developed for the determination of ribavirin in bulk and in its pharmaceutical preparations using alkaline potassium permanganate as an oxidizing agent. t...
Kinetic Determination of Acarbose and Miglitol in Bulk and Pharmaceutical Formulations Using Alkaline Potassium Permanganate
kinetic determination spectophotometry acarbose miglitol potassium permanganate pharmaceuti¬ cal analysis
2009/4/20
A simple and sensitive kinetic spectrophotometric method was established for the determination of acar¬bose and miglitol in bulk and in their pharmaceutical preparations using alkaline potassium p...
Kinetic Spectrophotometric Method For The Determination of Ketoprofen in Pharmaceuticals and Biological Fluids
kinetic spectrophotometry ketoprofen pharmaceutical preparations biological fluids
2009/4/20
A simple and sensitive kinetic method is described for the determination of ketoprofen in pure form, pharmaceuticals and biological fluids. The method utilizes an oxidative- coupling reaction based up...
Hydroxyl radical scavenging effects of guaiacol used in traditional dental pulp sedation：Reaction kinetic study
Hydroxyl radical scavenging effects guaiacol used traditional dental pulp sedation
2009/3/3
Guaiacol, which is a phenolic compound with a methoxy group and used in traditional dental pulp sedation, has the property of inducing cell proliferation. To clarify these mechanisms of guaiacol, th...
Kinetic characterization of the inhibition of purified cynomolgus monkey lactate dehydrogenase isozymes by gossypol
Kinetic characterization purified cynomolgus monkey dehydrogenase isozymes gossypol
2009/2/23
This report describes the results of the first step in a sequence of experiments designed to test the hypothesis that the sperm-specific isozyme of lactate dehydrogenase (LDH-C4), is a site of actio...