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The Autoimmune Diseases Manifested by Production of Autoantibodies:The Autoantigens Identified by Random Peptide Library
Autoantigens Autoimmune diseases Random peptide library
2009/12/11
Phage-displayed random peptide libraries (RPL) provide a powerful technique for identification, structural and functional analysis of ligands for many different target molecules, including, antibodies...
The Autoimmune Diseases Manifested by Production of Autoantibodies:The Autoantigens Identified by Random Peptide Library
Autoantigens Autoimmune diseases Random peptide library
2009/12/11
Phage-displayed random peptide libraries (RPL) provide a powerful technique for identification, structural and functional analysis of ligands for many different target molecules, including, antibodies...
The Use of Polypeptide Probes Selected From Artificial Peptide Libraries for the Recognition and Differentiation of DNA Sequences
Phage display mutation detection polypeptide probes
2009/7/1
In the novel approach suggested here, we examined the use of polypeptide probes selected from artificial peptide libraries for the identification of the differences in dsDNA sequences which are potent...
Analysis of Helper T Cell Responses to Cry j 1-Derived Peptides in Patients with Nasal Allergy: Candidate for Peptide-Based Immunotherapy of Japanese Cedar Pollinosis
Cry j 1 immunotherapy nasal allergy peptide Th response
2010/11/16
Our results suggest four Cry j 1-derived peptides (p61-80, p115-132, p206-225 and p337-353) may be considered to be the immunodominant T-cell epitopes of the Cry j 1 molecule, and can be useful for th...
Synthesis, development and preclinical comparison of two new peptide based freeze-dried kit formulation 99mTc-EDDA-Tricine-HYNIC-TOC and 99mTc-EDDA-Tricine-HYNIC-TATE for somatostatin receptor positive tumor scintigraphy
99mTc Somatostatin Tyr3-octreotide Tyr3-Octreotate HYNIC Kit formulation
2010/4/7
Somatostatin receptor (sstr) scintigraphy with [111In diethylenetriaminepentaacetic acid]-octreotide ([111In-DTPA]-OC) has became a routine diagnostic procedure in oncology. However, it suffers from s...
Non-specific activation of human eosinophil functional responses by vasoactive intestinal peptide
allergic inflammation eosinophil functional response signal transduction vasoactive intestinal peptide
2010/11/25
Eosinophils and neuropeptides are thought to play effector roles in allergic diseases, such as rhinitis; however, little is known about the biological effects of neuromediators, especially vasoactive ...
Inhibitory effect of olopatadine hydrochloride (KW-4679), a novel antiallergic drug, on peptide leukotriene release from human eosinophils
antiallergic drug human eosinophils leukotriene olopatadine
2010/11/25
Olopatadine hydrochloride (olopatadine; KW-4679), (Z)-11-[(3-dimethylamino)propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid monohydrochloride, is an antiallergic drug with selective and potent...
Formulation of an injectable implant for peptide delivery and mechanistic study of the effect of polymer molecular weight on its release behavior
Injectable implant Poly (lactide-co-glycolide) Molecular weight Release Erosion
2010/2/3
The effects of polymer molecular weight on drug release from erodible matrices are not well known. It would be more complicated for in-situ forming injectable implants that change gradually from liqui...
Positional Effect of Amino Acid Replacement on Peptide Antigens for the Increased IFN-γ Production from CD4T Cells
analogue peptide complementarity determining region 3 interferon gamma peptide antigens T-cell antigen receptor
2010/11/19
Background: Based on the fact that site-specific amino acid replacement on peptide antigens stimulated T cell clones to produce increased amount of IFN-γ, we investigated this structure-function relat...