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A Novel Missense Mutation, E1623G,in the Human Factor VIII Gene Associated With Moderate Haemophilia A
Hemophilia A Mutation Missense F8 protein human
2015/10/10
Introduction:: Haemophilia A is the most common inherited X-linked recessive bleeding disorder. The severity of the resultant bleeding diathesis depends on the FVIII levels associated with the mutatio...
Tissue Engineering Using Human Mineralized Bone Xenograft and Bone Marrow Mesenchymal Stem Cells Allograft in Healing of Tibial Fracture of Experimental Rabbit Model
Bone Xenograft Allograft Mesenchymal stem cells Healing Rabbit
2015/9/25
Background: Bone healing and its reconstruction in fractures, especially in long bones are of particular importance in regenerative medicine. This study compares the bone healing rate after a human xe...
Determination of mycophenolic acid in human plasma by high-performance liquid chromatography
Mycophenolic acid Mycophenolate mofetile Kidney transplant
2010/1/6
A simple, sensitive and reproducible HPLC method is presented for determination of mycophenolic acid(MPA) in human plasma. Samples were prepared after precipitation of the plasma protein by addition o...
In vitro inhibition of human erythrocyte Acetylcholinesterase activity by Zinc and Mercury
Acetylcholinesterase Human erythrocyte
2010/1/6
The effects of zinc and mercury on human erythrocyte acetylcholinestrase activity were studied. Blood used in this study was obtained from 24 apparently healthy individuals and after hemolysation, was...
Pattern secretion of matrix Metalloproteinases and their biological tissue inhibitors by human glomerular mesangial cells in culture
Metalloproteinases Mesangial cell Glomerulosclerosis
2010/1/5
The glomerular mesangial cells (GMC) play a central role in the synthesis and turnover of the glomerular mesangial matrix. The breakdown of the matrix likely depends on the balance between of a variet...
Protective effects of antioxidants on high Glucose-induced malfunctions in human glomerular mesangial cells
Mesangial cells High glucose extracellular matrix
2009/12/31
Altered functions of mesangial cells induced by high glucose concentrations are thought to play an important role in the pathogenesis of diabetic nephropathy. We therefore investigated the effect of h...
REPORT OF HUMAN CASES INFECTED WITH DICROCOELIUM DENDRITICUM IN THE RURAL AREAS
Dicrocoelium dendriticum Eosinophylia
2009/12/30
During a longitudinal health survey carried out in 42 villages in Gonbad Kavus, stool examinations have been conducted among 1240 persons. Infection with Dicrocoelium dendriticum has been observed amo...
Pre-Symptomatic Human Cytomegalovirus Disease Diagnosis in Renal Transplant Recipients by the Virus DNA PCR
Human cytomegalovirus (HCMV) Renal transplant recipient Iran
2009/12/28
Human cytomegalovirus (HCMV, CMV) is a major infectious complication of renal transplantation. The objective of this survey was to optimize and establish a polymerase chain reaction (PCR) technique fo...
MOLECULAR MODELLING OF HUMAN ALDEHYDE OXIDASE AND IDENTIFICATION OF THE KEY INTERACTIONS IN THE ENZYME-SUBSTRATE COMPLEX
Aldehyde oxidase Molecular modeling 3D-QSAR genetic algorithm
2009/12/25
Aldehyde oxidase (EC 1.2.3.1), a cytosolic enzyme containing FAD, molybdenum and iron-sulphur cluster, is a member of non-cytochrome P-450 enzymes called molybdenum hydroxylases which is involved in t...
Antioxidant Capacity of Plasma after Pomegranate Intake in Human Volunteers
Pomegranate antioxidants vitamin E
2009/12/18
Dietary antioxidants including phenolic compounds are believed to be effective nutrients in the prevention of oxidative stress related disease. Pomegranate has been used for centuries in ancient cultu...
A Further Insight into the Origin of Human T-Lymphotropic Virus Type 1 (HTLV-1) in Japan, Based on the Genotyping of ABCC11
Human T-Lymphotropic Virus Type 1 (HTLV-1) Japan
2010/12/10
A Further Insight into the Origin of Human T-Lymphotropic Virus Type 1 (HTLV-1) in Japan, Based on the Genotyping of ABCC11.
Investigation of the Inhibition Effects of Some Antibiotics on Human Erythrocyte Carbonic Anhydrase Isozymes
Carbonic anhydrase isozymes antibiotics inhibition
2009/7/2
In this study, the in vitro effects of some antibiotics on carbonic anhydrase (CA) isozymes have been investigated. Human erythrocyte CA-I and CA-II isozymes were separately purified by affinity chrom...
The Effects of Sodium Selenite on the Antioxidative Defence Mechanism of Human Hepatoma G2 Cell
Hepatoma G2 Sodium selenite Glutathione peroxidase Catalase Superoxide dismutase
2009/6/30
Human cells that live in biological harmony can become cancerous. As they do so, they engage in anaerobic respiration, undergo rapid cell growth and division according to nonmitotic rules, and importa...
Investigation of Various Terminal Carbohydrate Structures in Apolipoproteins of Human Serum Chylomicrons and VLDL
Lipoprotein apolipoprotein glycoprotein carbohydrate sequence
2009/6/30
The roles of terminal carbohydrate moieties of serum glycoproteins in their recognition and uptake by receptors and in their rapid removal from the circulation are well established. However, little is...
Analysis of ras Gene Mutation in Human Oral Tumours by Polymerase Chain Reaction and Direct Sequencing
Oral tumour PCR Direct sequencing Tobacco-specific nitrosamines
2009/6/29
Genetic alterations in proto-oncogenes or tumour suppressor genes are believed to be one of the key events in the multistage process of carcinogenesis. Activating point mutations occurring in either o...