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Applying Surface Plasmon Resonance to Monitor the IgE-Mediated Activation of Human Basophils
basophil biosensor histamine release IgE surface plasmon resonance
2010/11/17
When basophils were sensitized with antigen specific IgE, they immediately caused the increase of resonance angle (AR) in response to either anti-IgE antibody or corresponding antigens, even when they...
Suppressive effects of the Chinese herbal remedy Tripterygium wilfordii Hook f on eosinophilia and IgE hyperproduction in mice
eosinophilia immunoglobulin E Mesocestoides cortii mouse suppression Tripterygium wilfordii
2010/11/25
The effects of chloroform extract of Tripterygium wilfordii Hook f (TWH extract) on eosinophilia and IgE hyperproduction induced by Mesocestoides cortii infection were examined in BALB/c mice. Mice we...
Permeability of rat IgE across rat aortic endothelial cell is enhanced by histamine
IgE endothelial cells histamine permeability
2010/11/25
On the basis of results from the present study, histamine, acting via H2 receptors, enhances the permeability of rat IgE across the RAEC mono-layer. The increased permeability of endothelial cells ind...
Passive anaphylaxis and IgE antibody production are compromised in tumor necrosis factor- and in granulocyte-macrophage colony stimulating factor-deficient mice
granulocyte-macrophage colony stimulating factor-deficient mice IgE mast cell passive cutaneous anaphylactic reaction tumor necrosis factor-deficient mice
2010/11/25
Background: A number of recent studies has demonstrated a critical role for mast cells and mast cell-derived cytokines, especially tumour necrosis factor (TNF), in the control of host defense mechanis...
Differences in mast cell-bound IgE in the nasal epithelial layer and lamina propria
allergic rhinitis IgE immunohistochemistry mast cell nasal mucosa
2010/11/25
Mast cells in the allergic nasal mucosa are reported to have higher concentrations of high affinity type I Fcε receptors (FcεRI) than mast cells in the non-allergic mucosa. IgE binds to FcεRI on mast ...
Blocking the CD154-CD40 interaction with anti-CD154 antibody differentially regulates interleukin-4 synthesis in T cells and IgE production in B cells
CD154 CD40 germline Cε IgE interleukin-4
2010/11/25
Using severe combined immunodeficiency mice engrafted with peripheral blood mononuclear cells from atopic patients, we analyzed the regulatory effects of anti-CD154 antibody on the in vivo induction o...