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Study shows loss of gene function is causal to congenital heart disease（图）
loss of gene function causal congenital heart disease
2021/4/9
A team of researchers co-led by Michael Frohman of Stony Brook University has identified an important cause of congenital heart disease. The researchers discovered that certain loss of funct...
Serum response factor-dependent regulation of smooth muscle gene transcription
Smooth muscle cells Gene regulation MicroRNA Chromatin remodeling Serum Response Factor
2015/5/22
Several common diseases such as atherosclerosis, post-angioplasty restenosis, and graft vasculopathies, are associated with the changes in the structure and function of smooth muscle cells. During the...
EVALUATION OF GENE REGULATION AND THERAPEUTIC DRUGS RELATED TO ALZHEIMER’S DISEASE IN DEGENERATING PRIMARY CEREBROCORTICAL CULTURES
Alzheimer synapse neurodegeneration primary culture memantine
2015/5/21
Alzheimer’s disease (AD) is a neurological disorder defined by the presence of plaques comprised mostly of amyloid-β (Aβ), and neurofibrillary tangles consisting of hyperphosphorylated microtubule ass...
Gene links lower birth weight and type 2 diabetes（图）
Gene links birth weight type 2 diabetes
2010/4/29
Two gene regions that influence a baby’s weight at birth have been identified by a large international team of researchers, including scientists from Oxford University. One of the genes is also associ...
Association of Methylenetetrahydrofolate Reductase gene Polymorphism (C677T) with Metabolic Syndrome in an Iranian Population: Tehran Homocysteine Survey
MTHFR Metabolic syndrome Population
2009/11/26
Background: The association of MTHFR and metabolic syndrome (MS) has been shown in special groups of diabetic and schizophrenic subjects, but no single study has investigated this relation in metaboli...
Mice With Parkinson’s Disease Gene May Point the Way to New Treatments（图）
Mice Parkinson’s Disease Gene New Treatments
2009/6/23
Scientists at Weill Cornell Medical College have developed a new mouse model of Parkinson’s disease (PD) that successfully reproduces the impairments of movement and the degenerative brain changes tha...
Association between the Polymorphism of TGF-β1 Gene Promoter (-509C>T) and Idiopathic Chronic Urticaria
Polymorphism TGF-1 gene Urticaria
2010/2/1
Idiopathic Chronic Urticaria (ICU), the most common form (70-80%) of chronic urticaria is supposed to have immune basis causes. It is speculated that the promoter polymorphism of TGF-β1 gene may be in...
The Detection of Dopamine Gene Receptors (DRD1-DRD5) Expression on Human Peripheral Blood Lymphocytes by Real Time PCR
Dopamine Receptors Gene Expression Lymphocytes Polymerase Chain Reaction
2010/2/8
There is interrelationship between the immune and nervous systems that is accomplished by the molecular mediators. Dopamine is one of the most important neurotransmitters. Five different dopamine rece...