搜索结果: 1-14 共查到“临床医学 kinase”相关记录14条 . 查询时间(0.062 秒)
Decreased Activity in Neuropathic Pain Form and Gene Expression of Cyclin-Dependent Kinase5 and Glycogen Synthase Kinase-3 Beta in Soleus Muscle of Wistar Male Rats
Neuropathic Pain Soleus Muscle CDK5 Protein Kinase
2015/11/6
Background: The relationship between decreased activity/neuropathic pain and gene expression alterations in soleus muscle has remained elusive.
Efflux of Creatine Kinase from Isolated Soleus Muscle Depends on Age, Sex and Type of Exercise in Mice
Skeletal muscle eccentric contractions muscle damage CK activity
2015/8/28
Elevated plasma creatine kinase (CK) activity is often used as an
indicator of exercise-induced muscle damage. Our aim was to
study effects of contraction type, sex and age on CK efflux from
iso...
PROTEIN PHOSPHATASE 2A (PP2A) HOLOENZYMES REGULATE DEATH ASSOCIATED PROTEIN KINASE (DAPK) IN CERAMIDE-INDUCED ANOIKIS
PROTEIN PHOSPHATASE 2A DAPK DEATH ASSOCIATED PROTEIN KINASE
2015/5/22
Modulation of sphingolipid-induced apoptosis is a potential mechanism to enhance the effectiveness of chemotherapeutic drugs. Ceramide is a pleiotropic, sphingolipid produced by cells in response to i...
Death-Associated Protein Kinase Regulates Vascular Smooth Muscle Cell Signaling and Migration
p65 MMP9 atherosclerosis
2015/5/22
Cardiovascular disease is the number one cause of death for Americans. New treatments are needed for serious conditions like atherosclerosis, as it can lead to stroke and heart attack. Many types of c...
p21-activated kinase regulates mast cell degranulation via effects on calcium mobilization and cytoskeletal dynamics
mast cells Pak1 allergic diseasis
2014/12/12
Mast cells are key participants in allergic diseases via activation of high-affinity IgE receptors (FcϵRI) resulting in release of proinflammatory mediators. The biochemical pathways linking IgE...
The p21activated kinase 1 (PAK1) belongs to PAKs family, a group of highly evolutionarily conserved protein family of serine/threonine kinases, which acts as a downstream effector of the small GTPase...
Purification of Casein Kinase II From Lung Tissue and Kinetic Evaluations With Polyamines and Myc-Oncoprotein
Casein kinase II olyamines yc ell proliferation abbreviations KII-casein kinase II myc-phosphorylated myc oncoprotein Pmax-phosphorylated max protein
2009/7/2
The overall goal of this study was to seek molecular linkages between polyamines, casein kinase II, and the myc oncoprotein by using a cell-free, highly purified enzyme kinetic analysis. Casein kinase...
目的 探讨polo-like kinase-1（PLK1）基因对大肠癌细胞增殖和端粒酶活性的影响。 方法根据PLK1基因序列特点，设计并用化学方法合成小干扰核糖核酸分子（small interfering RNA，siRNA），转染人大肠癌SW480细胞后，分别采用实时定量PCR和Western blot检测PLK1基因mRNA和蛋白表达水平。分别采用MTT法和TRAP-ELISA方法检测PLK...
Inhibition of corneal neovascularization with new Tyrosine Kinase Inhibitors targeting vascular endothelial growth factor receptors:Sunitinib malate and Sorafenib
Cornea Sunitinib malate Sorafenib
2010/4/16
Corneal neovascularization (NV) is a significant, sight-threatening, complication of many ocular surface disorders. Presence of new vessels in cornea can compromise clarity and thus vision. The data s...
期刊信息
篇名
Role of Rho kinase and actin filament in the increased vascular permeability of skin venule in rat after scalding.
语种
英文
撰写或编译
撰写
作者
Zheng HZh,Zhao KS,Zhou BY,Huang QB
第一作者单位
刊物名称
Burns
页面
200...
期刊信息
篇名
Involvement of cyclin dependent kinase 5 and its activator p35 in staurosporine-induced apoptosis of cortical neurons.
语种
英文
撰写或编译
作者
BaifangZhang,Fangfang Peng,ZhangWen,Shen Han,ShaoboWu,Dong...
Role of protein kinase A in the inhibition of human mast cell histamine release by β-adrenergic receptor agonists
β-adrenergic receptor agonist histamine release human cultured mast cells protein kinase A protein kinase C
2010/11/24
Stimulation of mast cells induced the elevation of intracellular cytosolic free Ca2+ concentrations ([Ca2+]i) and the translocation of protein kinase C (PKC) from the cytosol to the cell membrane, fol...
The effects of genistein, a tyrosine kinase inhibitor on acute and chronic inflammation in diabetic mice
Diabetes Genistein Inflammation Mice Streptozotocin Tyrosine kinase
2010/2/3
The effects of tyrosine kinases on acute and chronic inflammation during diabetes are not fully determined. Therefore, the present study focuses on the effects of genistein, a tyrosine kinase inhibito...
Role of protein kinase C and calmodulin in histamine release in experimental filariasis
Brugia malayi calmodulin histamine lung mast cells Mastomys natalensis peritoneal mast cells protein kinase C
2010/11/29
The allergenic activity of 60 kDa antigen of Brugia malayi adult worm, due to its ability to release histamine from mast cells, has been previously reported by us. To determine the roles of protein ki...