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Inhibition of the Antigen Provoked Nasal Reaction by Second-generation Antihistamines in Patients with Japanese Cedar Pollinosis
allergic rhinitis epinastine hydrochloride fexofenadine hydrochloride nasal provocation rhinoscopy
2010/11/19
Background: Epinastine hydrochloride and fexofenadine hydrochloride, the second-generation antihistamines, are largely used in the indication of allergic rhinitis in Japan. The purpose of this study w...
Effects of olopatadine hydrochloride on the release of thromboxane B2 and histamine from nasal mucosa after antigen-antibody reaction in guinea pigs
allergic rhinitis chemical mediators guinea pigs olopatadine
2010/11/25
Background: Various mediators, such as thromboxane (TX) A2, peptide leukotrienes (P-LT) and histamine, are involved in allergic nasal obstruction. The aim of the present study was to investigate the m...