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Mast cells in the testis, epididymis and accessory glands of the rat：effects of neonatal steroid treatment
Mast cells rat neonatal steroid treatment
2009/2/23
Mast cells in the testis of control adult rats were found almost exclusively around subcapsular blood vessels. Discrete mast cells were distributed throughout the stroma of the epididymis and sex ...
Sertoli cell junctional complexes in gossypol-treated neonatal and adult guinea pigs
Sertoli cell gossypol-treated neonatal adult guinea pigs
2009/2/23
The effect of gossypol, an experimental male contraceptive agent, on the development and maintenance of the blood-testis barrier was determined by feeding gossypol daily to prepubertal and adult gui...
Effects of neonatal estrogen administration on rat testis development with particular reference to Sertoli cells
neonatal estrogen administration rat testis development Sertoli cells
2009/2/23
An ultrastructural and morphometric study of the testes in 15-, 22-, 45-, and 90-day-old neonatally estrogenized rats was performed. At 45 days of age, the Sertoli cells appeared immature in estroge...
The development of male reproductive organ abnormalities after neonatal exposure to tamoxifen is genetically determined
Neonate mice strains testicular infarction epididymitis
2009/2/18
Responses of the male reproductive organs to neonatal exposures of tamoxifen (Tx) were examined in seven different strains of mice (A/J, AKR/J, BALB/cAnN, C3H/HeJ, C57BL/6J, DBA/ 2J, and FVB/N). Mal...
Impaired germ cell development in the testes of immature rats with neonatal hypothyroidism
Gonocyte Sertoli cell thyroid hormone stereology optical disector germ cell number
2009/2/17
The induction of neonatal hypothyroidism from day 1 to day 25 postpartum using 6-propyl-2-thiouracil (PTU) resulted in a 45% and 77% reduction of testis weight on days 20 and 30, respectively, and a...
Increased proliferation of Leydig cells induced by neonatal hypothyroidism in the rat
Propylthiouracil goitrogen cell kinetics ontogeny mitosis puberty
2009/2/16
Treatment of male rat pups with the reversible goitrogen 6-n-propyl-2-thiouracil (PTU), administered by adding 0.1% PTU to the mother's drinking water from birth through weaning, increases adult t...
NCAM mediates adhesion between gonocytes and Sertoli cells in cocultures from testes of neonatal rats
Testicular development Sertoli-.germ cell interaction
2009/2/13
During neonatal development of the rat testis, gonocytes resume mitosis and display renewed motility to migrate toward the basal lamina, two events that occur in vitro when these cells are coculture...
Effect of mesenchymal glandular inductors on the growth and cytodifferentiation of neonatal mouse seminal vesicle epithelium
mesenchymal glandular inductors cytodifferentiation neonatal mouse seminal vesicle epithelium
2009/2/13
To investigate the developmental properties of glandular mesenchymal inductors along the cranial-caudal extent of the developing male urogenital tract, neonatal mouse seminal vesicle epithelium (S...
Neonatal goitrogen treatment increases adult testis size and sperm production in the mouse
Testis propylthiouracil Sertoli cells hypothyroidism
2009/2/12
Male rats made hypothyroid during neonatal life show unprecedented increases in adult testis size and daily sperm production (DSP). To determine if this effect was unique to the rat or could also ...
Inhibition of steroidogenesis in neonatal Leydig cells by unknown factor（s）present in spent media of androgen-treated cultured testicular cells from adult rats
Leydig cell 5a-dihydrotestosterone methyltrienolone
2009/2/12
Treatment of cultured testicular cells from adult rats with 5 alpha-dihydrotestosterone (DHT; 10(-6) M) or the synthetic androgen methyltrienolone (R1881; 10(-6) M) inhibited Leydig cell 3 beta-hy...
Insulin-like growth factor 1, but not growth hormone, has in vitro proliferative effects on neonatal foreskin fibroblasts without affecting 5-alpha-reductase or androgen receptor activity
5-a-Reductase androgen receptor micropenis
2009/2/11
Clinical observation of patients with congenital growth hormone (GH) deficiency and Laron-type dwarfism suggests that factors such as GH or insulin-like growth factor 1 (IGF-1) might in addition to ...
Use of neonatal tolerization and chemical immunosuppression for the production of monoclonal antibodies to maturation-specific sperm surface molecules
neonatal tolerization chemical immunosuppression monoclonal antibodies
2009/2/7
Mammalian sperm acquire functional maturity as they move from the caput to the cauda epididymidis. Changes occur in the protein/glycoprotein composition of the sperm plasma membrane during this time...
Expression of Notch pathway components in spermatogonia and Sertoli cells of neonatal mice
Cell fate delta jagged presenilin spermatogenesis
2008/12/29
Members of the Notch gene family have been shown to play an important role in the control of cell fate in many developmental systems. We hypothesized that the fate of the male germ line stem cells m...
Thyroid hormone receptors in neonatal, prepubertal, and adult rat testis
Thyroid hormone receptors adult rat testis
2008/12/26
Thyroid hormone (TH) is involved in the differentiation and development of rat testis, whereas its role in adult testis function is still undefined. The aim of our work has been to further analyze the...
Effects of Ethanol on Embryonic and Neonatal Rat Testes in Organ Cultures
Gonocytes Sertoli cells testis seminiferous cords apoptosis
2008/12/19
Ethanol exposure in adult animals and humans has shown to elicit significant inhibitory effects on the function of male reproduction, but consequences of ethanol exposure on the embryonic and early ...