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Cholesterol-metabolism study suggests new diagnostic, treatment approach for aggressive prostate cancer(图)
diagnostic prostate cancer
2014/3/20
WEST LAFAYETTE, Ind. - Researchers have discovered a link between prostate cancer aggressiveness and the accumulation of a compound produced when cholesterol is metabolized in cells, findings that cou...
Exploring new territories: dialogues on comprehensive sexuality education
Sexual rights Young people adolescents
2014/3/28
Comprehensive sexuality education views sexuality as a positive force and celebrates diversity. However, we still need to explore the mosrt effective ways to translate our rights-based approach into t...
Cyclophosphamide in the male rat:new pattern of anomalies in the third generation
Cyclophosphamide male rat anomalies third generation
2009/2/23
Several abnormalities, such as postnatal deaths and behavioral impairments, have been previously reported in the progeny of male rats exposed to the cytostatic drug cyclophosphamide 60 days prior to...
Decrease in the number of human Ap and Ad spermatogonia and in the Ap/ Ad ratio with advancing age. New data on the spermatogonial stem cell
human testis spermatogonia aging
2009/2/23
The numbers of Ap and Ad spermatogonia per unit section of the testis were calculated in autopsy specimens from young adults and elderly men without testicular pathology. The number of Ap spermatogo...
Polarized Sertoli cell functions in a new two-compartment culture system
Polarized Sertoli cell functions new two-compartment culture system
2009/2/23
Sertoli cells in vivo are highly polarized and interact with the inner (tubular) and outer (interstitial) fluids. To simulate this condition in vitro we developed a two-compartment culture system ...
Tubular patency is the primary concern in the evaluation of procedures for epididymovasostomy. The epididymal lumen easily becomes occluded or obstructed, with the resulting recurrence of azoospermi...
Pure Sertoli Cell Cultures:A New Model for the Study of Somatic-Germ Cell Interactions
cell cultures Sertoli cell germ cell
2009/2/19
A new technique involving a brief hypotonic treatment was developed for obtaining pure rat Sertoli cell cultures. This method for the selective removal of the germ cells present in Sertoli cell enri...
A new method to generate canine seminal emission and its application to men:direct electrical stimulation of the vas deferens
generate canine seminal emission direct electrical stimulation vas deferens
2009/2/12
Seminal emission from the ejaculatory duct (SEED) by direct electrical stimulation of the vas deferens was investigated in the dog, and the technique was applied to men. The stimulus parameters used w...
A new approach to study the architectural arrangement of spermatogenic stages revealed little evidence of a partial wave along the length of human seminiferous tubules
architectural arrangement spermatogenic stages revealed little evidence partial wave human seminiferous tubules
2009/2/12
Although evidence of the spermatogenic wave in humans has been reported, little is known about the architectural arrangement of stages along the length of tubules in men with varied rates of sperm p...
Atamestane, a new aromatase inhibitor for the management of benign prostatic hyperplasia
aromatase inhibitor management benign prostatic hyperplasia
2009/2/7
Atamestane is a new, competitive, and irreversible inhibitor of estrogen biosynthesis. Its pharmacologic action has been evaluated in mice, rats, rabbits, dogs, monkeys, and humans. In rats, atame...
Characterization of a new superfusion, two-compartment culture system for Sertoli cells:influence of extracellular matrix on the cell permeability and dynamics of transferrin secretion
two compartment culture system sertoli
2009/2/6
A new superfusion two-compartment culture system was developed in the laboratory of the author and was used to investigate the influence of testicular extracellular matrix on barrier formation by Se...
Properties of a new, long-lasting vaginal delivery system(LASRS)for contraceptive and antimicrobial agents
vaginal delivery system contraceptive antimicrobial agents
2008/12/26
In view of the need for improved vaginal formulations that are contraceptive, that may prevent transmission of sexually transmitted infections, or both, a new delivery system (base formulation; call...
Mouse Spam1(PH-20):evidence for its expression in the epididymis and for a new category of spermatogenic-expressed genes
Mouse Spam epididymis spermatogenic-expressed genes
2008/12/25
The gene for the sperm adhesion molecule 1 (PH-20), SPAM1, has been known to be testis-specific and exclusively haploid expressed. We show that in mice, the 2 common isoforms of the protein (Spam1...
Changes in Testosterone and Dihydrotestosterone Levels in Male Rat Accessory Sex Organs, Serum, and Seminal Fluid After Castration:Establishment of a New Highly Sensitive Simultaneous Androgen Measurement Method
LC-MS/MS hormone prostate seminal vesicles
2008/12/23
It is known that abnormal androgen dynamics in the tissues is a cause of androgen-dependent disorders. Investigation of tissue androgen levels could provide a clue to the elucidation of disorders....
Between the wars on terror and in Iraq, the ubiquitous presidential politics, and the celebrity trials, little else has recently engendered notable television or print news attention. One such unfortu...