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The pattern of LH release in the adult ram influences the testicular steroidogenic response to individual LH pulses and is regulated by testosterone negative feedback
LH release adult ram influences testicular steroidogenic individual LH pulses
2009/2/23
Two experiments were conducted with adult intact rams (approximately 58 kg in body weight) in the nonbreeding season to investigate interrelationships between LH and testosterone secretion. In Exp...
Response to acute hCG stimulation and steroidogenic potential of Leydig cell fibroblastic precursors in humans
acute hCG stimulation steroidogenic potential Leydig cell fibroblastic precursors humans
2009/2/20
The process of early testosterone (T) secretion and Leydig cell differentiation in humans was studied to explore the steroidogenic capacity of Leydig cell fibroblastic precursors. Seven cryptorchi...
Is Leydig cell steroidogenic function affected by the germ cell content of the seminiferous tubules?
Leydig cell steroidogenesis
2009/2/17
The effect of testicular germ cell content on Leydig cell steroidogenic function in vivo in adult rats was examined. Three experimental paradigms were used to effect germ cell changes. First, a vita...
Are Leydig cell steroidogenic enzymes differentially regulated with aging?
Leydig cells aging steroidogenesis
2009/2/16
Previous studies have shown that the ability of Brown Norway rat Leydig cells to produce testosterone declines significantly with age. To address the possible mechanism(s) by which aging Leydig cell...
Prenatal exposure to dexamethasone alters Leydig cell steroidogenic capacity in immature and adult rats
Testis neuroendocrine luteinizing hormone testosterone
2008/12/29
This study examines the effects of prenatal exposure to dexamethasone (DEX) on postnatal testosterone production in male rats. Pregnant female rats were treated on gestation days 14-19 with DEX (1...
Melatonin inhibits the expression of steroidogenic acute regulatory protein and steroidogenesis in MA-10 cells
Melatonin inhibits steroidogenic protein steroidogenesis MA-10 cells
2008/12/26
The effects of melatonin on steroidogenesis and steroidogenic acute regulatory (StAR) protein expression were investigated in MA-10 mouse Leydig tumor cells. MA-10 cells were treated with human chorio...
Leydig cell aging：steroidogenic acute regulatory protein（StAR）and cholesterol side-chain cleavage enzyme
Leydig cell aging protein（StAR） cholesterol side-chain cleavage enzyme
2008/12/26
Primary points of control in steroidogenesis are the transport of cholesterol from intracellular stores to the inner mitochondrial membrane, and the subsequent conversion of cholesterol to pregnenolon...
Temporal Relationships Among Testosterone Production, Steroidogenic Acute Regulatory Protein (StAR), and P450 Side-Chain Cleavage Enzyme（P450scc）During Leydig Cell Aging
Leydig cell cyclic AMP steroidogenesis Brown Norway rat
2008/12/22
Previous studies have shown that the capacity of Leydig cells from aged (21-24-month-old) Brown Norway rats to produce testosterone is reduced from young (4-month-old) levels, and that this is cor...