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Data suggests stopping immunotherapy after two years is reasonable in patients with advanced lung cancer（图）
晚期肺癌 免疫治疗 停止治疗
2023/6/27
Over the past decade, the approval of immune checkpoint inhibitors has revolutionized treatment for patients with advanced lung cancer, helping many live longer lives and improving overall survival fo...
Evolution of biological therapies in non-small cell lung cancer
biological therapies non-small cell lung cancer
2015/3/26
This article explores recent clinical developments of biological or targeted therapies in non-small cell lung cancer. Molecular research has given us a greater understanding of tumour biology and has ...
Non-small cell lung cancer in the elderly - systemic therapy
Non-small cell lung cancer elderly - systemic therapy
2015/3/26
Elderly patients represent a significant and rising proportion of patients with Non-Small Cell Lung Cancer and historically they have been under-treated and under-represented in clinical trials. Incre...
Systemic therapy of lung cancer: where are we in 2002?
Systemic therapy lung cancer where are we in 2002
2015/3/11
At a time when our understanding of the molecular biology of cancer was supposed to lead to major advances in therapy, it is disappointing to report that the major lung cancer ‘story’ of 2002 (table o...
Sleep Duration and Risk of Lung Cancer in the Physicians' Health Study
Sleep Duration Risk Lung Cancer Physicians' Health Study
2014/9/29
Background and Objectives: Lung cancer is the most common cancer and cancer related cause of death worldwide. However, the association between sleep duration and incident lung cancer has not been inve...
Menstrual Factors, Reproductive Factors
and Lung Cancer Risk: A Meta-analysis
Lung neoplasms Age at menarche Length of menstrual cycle Female sex hormones
2013/12/4
Background and objective Epidemiological studies have suggested that menstrual and reproductive factors may influence lung cancer risk, but the results are controversial. We therefore carried out a me...
MicroRNAs (miRNAs) are a class of non-coding RNAs that hybridize to mRNAs and induce either translation repression or mRNA cleavage. Recently, it has been reported that miRNAs could possibly play a cr...
Pemetrexed in Previously Treated Non-small Cell Lung Cancer Patients with Poor Performance Status
Pemetrexed Lung neoplasms Poor performance
2013/12/6
Background and objective Pemetrexed have been approved for the treatment of patients affected by advanced non-small cell lung cancner (NSCLC) in progression after first-line chemotherapy. We evaluated...
Prospective Analysis on Survival Outcomes of Nonsmall Cell Lung Cancer Stages over IIIb Treated with HangAm-Dan
Lung neoplasms HangAm-Dan Oriental medicine Overall survival rate Cancer Herb
2013/12/6
Background and objective Non-small cell lung cancer (NSCLC) stages over IIIb still remain as an intractable disease. Survival rate of NSCLC stages over IIIb could be increased through chemotherapy and...
The Relationships between cyclin D1 Expression and Prognosis of Non-small Cell Lung Cancer
Lung neoplasms cyclin D1 Prognosis Immunohistochemistry
2013/12/6
Background and objective cyclin D1 is a member of the cyclin family, and it has been proven that it plaied an important role in tumorigenesis, invasion and metastasis. We performed a retrospective stu...
Surgical Therapeutic Strategy for Non-small Cell Lung Cancer with Mediastinal Lymph Node Metastasis (N2)
Lung neoplasms Thoracic surgical procedures Lymphatic metastasis Treatment outcome
2013/12/9
Background and objective Approximately 30% of patients who are diagnosed with non-small cell lung cancer (NSCLC) are classified as N2 on the basis of metastasis to the mediastinal lymph nodes. The eff...
Heparanase Expression Correlates with Angiogenesis and Lymphangiogenesis in Human Lung Cancer
Lung Neoplasms Heparanase Vascular Endothelial Growth Factor-C Lymphatic Metastasis
2013/12/10
Background and objective Heparanase has been thought to be a good molecular marker of tumor, and the heparanase expression level correlated closely with tumor metastasis. In this study, we investigate...
Gene Polymorphisms and Chemotherapy in Non-small Cell Lung Cancer
Lung neoplasms Genetic polymorphism Drug therapy
2013/12/10
The phamacogenetics is being used to predict whether the selected chemotherapy will be really effective and tolerable to the patient. Irinotecan, oxidized by CYP3A4 to produce inactive compounds, is u...
WEEKLY ASSESSMENT OF QUALITY OF LIFE IN PATIENTS WITH ADVANCED NON-SMALL-CELL LUNG CANCER DURING CHEMOTHERAPY IN A RANDOMIZED PHASE III TRIAL
Adverse event chemotherapy lung cance non-small-cell phase III trial quality of life
2009/7/15
This study investigated quality of life (QOL) in patients with advanced non-small-cell lung cancer in an early phase of chemotherapy in a randomized phase III trial. QOL assessments for four domains (...
End of Life Experience of Symptom Cluster and Their Management in Hong Kong Chinese Patients with Lung Cancer Who Receive Palliative Radiotherapy
End of life care lung neoplasms Palliative radiotherapy Fatigue Anxiety Breathlessness
2013/12/10
Breathlessness, fatigue, and anxiety are distressing symptoms for patients with advanced lung cancer, however, they are not relieved by palliative RT and are often viewed as neglected areas of clinica...