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Novel pooled testing strategies can significantly improve detection of COVID-19（图）
pooled testing strategies significantly improve detection COVID-19
2021/3/12
A new approach to pooled COVID-19 testing can be a highly effective tool for curbing the pandemic even if infections are widespread in a community, according to researchers at the Harvard University T...
Gemcitabine, lycorine and oxysophoridine inhibit novel coronavirus (SARS-CoV-2) in cell culture
Novel coronavirus alkaloid broad-spectrum antiviral 2019-nCoV SARS-CoV-2
2020/6/11
The emerging SARS-CoV-2 infection associated with the outbreak of viral pneumonia in China is ongoing worldwide. There are no approved antiviral therapies to treat this viral disease. Here we examined...
Rapid and visual detection of 2019 novel coronavirus (SARS-CoV-2) by a reverse transcription loop-mediated isothermal amplification assay
SARS-CoV-2 RT-LAMP COVID-19 Detection Visual
2020/6/12
To evaluate a reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay for detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and compare it with RT-PCR.
Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody
2019-nCoV SARS-CoV ACE2 monoclonal antibody RBD
2020/6/12
The newly identified 2019 novel coronavirus (2019-nCoV) has caused more than 11,900 laboratory-confirmed human infections, including 259 deaths, posing a serious threat to human health. Currently, how...
Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro
Remdesivir chloroquine effectively inhibit novel coronavirus (2019-nCoV) vitro
2020/6/12
In December 2019, a novel pneumonia caused by a previously unknown pathogen emerged in Wuhan, a city of 11 million people in central China. The initial cases were linked to exposures in a seafood mark...
Odd-chain fatty acids as a biomarker for dietary fiber intake: a novel pathway for endogenous production from propionate
soluble fiber fermentation pentadecanoic heptadecanoic liver long-chain fatty acid
2018/11/14
Background: The risk of type 2 diabetes is inversely correlated with plasma concentrations of odd-chain fatty acids [OCFAs; pentadecanoic acid (15:0) and heptadecanoic acid (17:0)], which are consider...
A novel extrinsic reference method for assessing the vitamin A value of plant foods
carotenoid bioavailability vitamin A retinol equivalency
2016/6/14
The amounts of vitamin A that are metabolically
derived from specific carotene-containing foods are largely
unknown.
A novel source of wheat fiber and protein: effects on fecal bulk and serum lipids
Wheat bran wheat protein fecal bulk
2016/5/30
Wheat fiber is a laxative and wheat protein may
affect blood lipids.
A novel cut-off for abdominal obesity derived from various anthropometric indices to predict body composition: arm fat area
Adolescents anthropometry epidemiology fat overweight prevalence and indicators
2010/10/14
Determination of fat and fat-free mass is of considerable interest in evaluation of nutritional status. The aim of the present study was to determine whether using arm fat area (AFA) is helpful in ide...
Preclinical and phase 1 clinical safety of Setarud (IMODTM), a novel immunomodulator
Setarud IMODTM Acute toxicity Chronic toxicity Maximum Tolerated DoseDARU
2009/12/2
Background: A new herbal drug, Setarud (IMODTM) that has been shown to have beneficial immune effects was tested to determine its acute and chronic toxicity in animals and to establish its intravenous...
A high-fat meal induces low-grade endotoxemia：evidence of a novel mechanism of postprandial inflammation1,2,3
Atherosclerosis endotoxin inflammation diet postprandial lipemia smoking
2008/12/25
Background: Bacterial endotoxin is a potently inflammatory antigen that is abundant in the human gut. Endotoxin circulates at low concentrations in the blood of all healthy individuals, although eleva...
Associations between diet and disease activity in ulcerative colitis patients using a novel method of data analysis
disease activity diet Associations
2008/4/23
The relapsing nature and varying geographical prevalence of ulcerative colitis (UC) implicates environmental factors such as diet in its aetiology.
A novel dual radio- and stable-isotope method for measuring calcium absorption in humans: comparison with the whole-body radioisotope retention method
Calcium absorption radioisotopes 47Ca
2016/12/29
The objective was to compare a dual-isotope method combining radioisotopes and stable isotopes with a whole-body radioisotope retention method for measuring calcium absorption.
Fortification of orange juice with vitamin D: a novel approach for enhancing vitamin D nutritional health
Vitamin D deficiency milk orange juice
2017/1/3
Fortification of milk with vitamin D may not be adequate for satisfying the vitamin D requirement because of variability in vitamin D content after fortification and because many persons have milk all...
Effect of a 28-d treatment with L-796568,a novel β3-adrenergic receptor agonist,on energy expenditure and body composition in obese men
L-796568 β3-adrenergic recepto β3-adrenergic receptor agonist β3-adrenergic selectivity energy expenditure lipolysis respiratory quotient indirect calorimetry triacylglycerol obesity obese men
2016/12/19
Background: Stimulation of energy expenditure (EE) with selective thermogenic β-adrenergic agonists may be a promising approach for treating obesity.
Objective: We analyzed the effects of t...