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二甲双胍作为最常用的降糖药物,已经被报道在多种肿瘤中可作为潜在的抗肿瘤药物。然而,由于二甲双胍的具体作用靶点不明确,极大地限制了我们对二甲双胍的理解和应用,并且二甲双胍在不同亚型的肿瘤中疗效并不相同。
Iron-Induced Cerebellar Purkinje Cell Loss Is Ameliorated by Flunarizine
Flunarizine iron neurotoxicity Purkinje cell stereology
2009/5/21
Aim: In this study, we investigated the effect of intracerebroventricular-injected iron neurotoxicity on the total number of cerebellar Purkinje cells in rats and the possible neuroprotective effect o...