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Earlier Alzheimer’s diagnosis may be possible with new imaging compound
Earlier Alzheimer diagnosis imaging compound
2016/11/29
By the time unambiguous signs of memory loss and cognitive decline appear in people with Alzheimer’s disease, their brains already are significantly damaged, dotted with clumps of a destructive protei...
Understanding the individual with Alzheimer’s disease: Can socioemotional selectivity theory guide us?
Alzheimer’s Disease Socioemotional Selectivity Theory Individual Differences Awareness Positivity Bias Socialization
2013/1/28
Individuals often get lost behind the diagnosis of Alzheimer’s disease (AD) while widespread differences between these patients are more common than similarities. Socioemotional Selectivity Theory (SS...
Certain new aspects of etiology and pathogenesis of Alzheimer’s disease
Alzheimer's Disease CDR TDR Dementia Vascular Factors in Alzheimer’s Disease
2013/1/28
The research focuses on the possibility of early detection of AD-specific vascular and atrophic brain changes in families which have a tendency to inherit the disease. The research included three fami...
Comparison of protein concentrations in serum versus plasma from Alzheimer’s patients
Alzheimer’s Disease Serum Proteins Plasma Proteins
2013/1/28
Background: There is great interest in developing blood-based biomarkers for Alzheimer’s disease (AD); however, there is no consensus as to what blood fraction is most appropriate for analyzing partic...
Prevalence of cerebrospinal fluid Alzheimer disease-like pattern in atypical dementias
CSF Alzheimer Disease Atypical Dementias Frontotemporal Dementia Corticobasal Syndrome Progressive Supranuclear Palsy
2013/1/28
BACKGROUND: Differential diagnosis between Frontotemporal Dementia (FTD), Corticobasal Syndrome (CBS), Progressive Supranuclear Palsy Syndrome (PSP), FTD with motor neuron disease (FTD-MND) is often c...
CSF tau and amyloid β42 levels in Alzheimer’s disease—A meta-analysis
Alzheimer’s Disease Dementia CSF Amyloid β42 CSF Tau Meta-Analysis
2013/1/28
Alzheimer’s disease International (ADI) estimates that there are currently 30 million people with dementia in the world. The main objective was to perform meta-analysis of studies of CSF tau and Amylo...
Neural correlates of focused attention in patients with mild Alzheimer’s disease
fMRI Focused Attention Stroop Alzheimer’s Disease
2013/2/20
Alzheimer’s Disease (AD) is characterized by an early and significant memory impairment, and progresses to affect other cognitive domains. Impairments in Focused Attention (FA) have been observed in p...
Elevated levels of 4-hydroxynonenal-histidine Michael adduct in the hippocampi of patients with Alzheimer's disease
Elevated levels 4-hydroxynonenal-histidine Michael Alzheimer's disease
2009/12/16
Alzheimer's disease (AD) is among the most common causes of progressive cognitive impairment in humans and is characterized by neurodegeneration in the brain. Lipid peroxidation is thought to play a r...
Alois Alzheimer: a hundred years after the discovery of the eponymous disorder
Alois Alzheimer hundred years discovery eponymous disorder
2009/4/20
The familiar term "Alzheimer's disease" was coined by Emil Kraepelin to honour his pupil, Alois Alzheimer. However, little is known about the life of the man after whom this important and well-kn...